Effets of ethanol and diazepan on ag-nor neuronal activity in the medial mammillary nucleus

  1. Santín Núñez, Luis Javier 1
  2. Rubio Fernández, Sandra María 1
  3. García Moreno, Luis Miguel 1
  4. González Pardo, Héctor 1
  5. Arias Pérez, Jorge Luis 1
  1. 1 Universidad de Oviedo
    info

    Universidad de Oviedo

    Oviedo, España

    ROR https://ror.org/006gksa02

Revista:
Psicothema

ISSN: 0214-9915

Año de publicación: 1993

Volumen: 5

Número: 1

Páginas: 125-134

Tipo: Artículo

Otras publicaciones en: Psicothema

Resumen

Efectos del etanol y el diazepan sobre la actividad Ag-NOR neuronal en el núcleo mamilar medial. Se pretende estudiar las alteraciones producidas en los mamilares tanto a nivel conductual como a nivel morfológico tras la administración de diazepam y alcohol. Para ello se emplearon 3 grupos de ratas testadas en la prueba del laberinto en T de agua. Uno de los grupos tratado con diazepam, otro grupo alcoholizado y un tercer grupo control. Se registraron los tiempos de reacción y los errores cometidos el ultimo día. El estudio histológico consistió en la determinación del número de Ag-NORs y el área de los mismos en cada núcleo neuronal. Los resultados muestran una disminución en el tiempo de reacción estadísticamente significativa a lo largo del aprendizaje, sin existir apenas errores. No aparecen diferencias en el área NORs estimada en los grupos experimentales. Sin embargo, se muestran diferencias en el número de NORs cuantificados entre los distintos grupos tratados en relación al grupo control

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