Publicaciones (60) Publicaciones de FRANCISCO JAVIER LACADENA GARCÍA-GALLO

2023

  1. A New Optimized Version of a Colorectal Cancer-Targeted Immunotoxin Based on a Non-Immunogenic Variant of the Ribotoxin α-Sarcin

    Cancers, Vol. 15, Núm. 4

  2. Nanobody-Based EGFR-Targeting Immunotoxins for Colorectal Cancer Treatment

    Biomolecules, Vol. 13, Núm. 7

2022

  1. Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer

    Oncoimmunology, Vol. 11, Núm. 1, pp. 2034355

2021

  1. Antibody-based immunotoxins for colorectal cancer therapy

    Biomedicines, Vol. 9, Núm. 11

2020

  1. Der p 1-based immunotoxin as potential tool for the treatment of dust mite respiratory allergy

    Scientific Reports, Vol. 10, Núm. 1

2019

  1. A novel Carcinoembryonic Antigen (CEA)-Targeted Trimeric Immunotoxin shows significantly enhanced Antitumor Activity in Human Colorectal Cancer Xenografts

    Scientific Reports, Vol. 9, Núm. 1

  2. AMP-activated protein kinase: exploring new activators

    XIII Congreso de Investigación para estudiantes pregraduados de Ciencias de la salud. XVII Congreso de Ciencias veterInarias y Biomédicas: libro de actas (Universidad Complutense de Madrid), pp. 218-225

  3. Inclusion of a Furin Cleavage Site Enhances Antitumor Efficacy against Colorectal Cancer Cells of Ribotoxin α-Sarcin- or RNase T1-Based Immunotoxins

    Toxins, Vol. 11, Núm. 10

2017

  1. Fungal ribotoxins: A review of potential biotechnological applications

    Toxins, Vol. 9, Núm. 2

  2. Minimized natural versions of fungal ribotoxins show improved active site plasticity

    Archives of Biochemistry and Biophysics, Vol. 619, pp. 45-53

2016

  1. A deimmunised form of the ribotoxin, α-sarcin, lacking CD4+ T cell epitopes and its use as an immunotoxin warhead

    Protein Engineering, Design and Selection, Vol. 29, Núm. 11, pp. 531-540

  2. Involvement of loop 5 lysine residues and the N-terminal β-hairpin of the ribotoxin hirsutellin A on its insecticidal activity

    Biological Chemistry, Vol. 397, Núm. 2, pp. 135-145

  3. Synergistic action of actinoporin isoforms from the same sea anemone species assembled into functionally active heteropores

    Journal of Biological Chemistry, Vol. 291, Núm. 27, pp. 14109-14119

2015

  1. Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin α-sarcin in nude mice bearing human colorectal cancer xenografts

    SpringerPlus, Vol. 4, Núm. 1

  2. Involvement of loops 2 and 3 of α-sarcin on its ribotoxic activity

    Toxicon, Vol. 96, pp. 1-9

  3. Preparation of an engineered safer immunotoxin against colon carcinoma based on the ribotoxin hirsutellin A

    FEBS Journal, Vol. 282, Núm. 11, pp. 2131-2141

  4. α-sarcin and RNase T1 based immunoconjugates: The role of intracellular trafficking in cytotoxic efficiency

    FEBS Journal, Vol. 282, Núm. 4, pp. 673-684

2014

  1. Efficient production of single-chain fragment variable-based N-terminal trimerbodies in Pichia pastoris

    Microbial Cell Factories, Vol. 13, Núm. 1

2013

  1. Hirsutellin A: A paradigmatic example of the insecticidal function of fungal ribotoxins

    Insects, Vol. 4, Núm. 3, pp. 339-356

2012

  1. A non-cytotoxic but ribonucleolytically specific ribotoxin variant: Implication of tryptophan residues in the cytotoxicity of hirsutellin A

    Biological Chemistry, Vol. 393, Núm. 6, pp. 449-456