JOSÉ ANTONIO ESCARIO GARCÍA-TREVIJANO-rekin lankidetzan egindako argitalpenak (64)

2022

  1. 5-Nitroindazole-based compounds: further studies for activity optimization as anti-Trypanosoma cruzi agents

    Acta Tropica, Vol. 234

  2. Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis

    Journal of enzyme inhibition and medicinal chemistry, Vol. 37, Núm. 1, pp. 781-791

2021

  1. Promising hit compounds against resistant trichomoniasis: Synthesis and antiparasitic activity of 3-(ω-aminoalkoxy)-1-benzyl-5-nitroindazoles

    Bioorganic and Medicinal Chemistry Letters, Vol. 37

2020

  1. Activity profile of two 5-nitroindazole derivatives over the moderately drug-resistant Trypanosoma cruzi y strain (DTU TcII): In vitro and in vivo studies

    Parasitology, Vol. 147, Núm. 11, pp. 1216-1228

2018

  1. Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2-Benzyl-5-nitroindazole-Derived Amines

    ChemMedChem, Vol. 13, Núm. 12, pp. 1246-1259

  2. Drug repositioning for novel antitrichomonas from known antiprotozoan drugs using hierarchical screening

    Future Medicinal Chemistry, Vol. 10, Núm. 8, pp. 863-878

  3. Experimental models in Chagas disease: a review of the methodologies applied for screening compounds against Trypanosoma cruzi

    Parasitology Research, Vol. 117, Núm. 11, pp. 3367-3380

2017

  1. Novel Imidazo[4,5-c][1,2,6]thiadiazine 2,2-dioxides as antiproliferative trypanosoma cruzi drugs: Computational screening from neural network, synthesis and in vivo biological properties

    European Journal of Medicinal Chemistry, Vol. 136, pp. 223-234

2016

  1. Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles

    European Journal of Medicinal Chemistry, Vol. 115, pp. 295-310

  2. Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes

    Parasitology, Vol. 143, Núm. 11, pp. 1469-1478

  3. In vitro trichomonacidal activity and preliminary in silico chemometric studies of 5-nitroindazolin-3-one and 3-alkoxy-5-nitroindazole derivatives

    Parasitology, Vol. 143, Núm. 1, pp. 34-40

2015

  1. Bond-based bilinear indices for computational discovery of novel trypanosomicidal drug-like compounds through virtual screening

    European Journal of Medicinal Chemistry, Vol. 96, pp. 238-244

  2. Novel solid dispersions of benznidazole: Preparation, dissolution profile and biological evaluation as alternative antichagasic drug delivery system

    Experimental Parasitology, Vol. 149, pp. 84-91

  3. Sequestration of host-CD59 as potential immune evasion strategy of Trichomonas vaginalis

    Acta Tropica, Vol. 149, pp. 1-7

  4. Synthesis and in vitro and in vivo biological evaluation of substituted nitroquinoxalin-2-ones and 2,3-diones as novel trichomonacidal agents

    European Journal of Medicinal Chemistry, Vol. 94, pp. 276-283

2014

  1. A sequential procedure for rapid and accurate identification of putative trichomonacidal agents

    Journal of Microbiological Methods, Vol. 105, pp. 162-167

  2. Antiprotozoan lead discovery by aligning dry and wet screening: Prediction, synthesis, and biological assay of novel quinoxalinones

    Bioorganic and Medicinal Chemistry, Vol. 22, Núm. 5, pp. 1568-1585

  3. Determination of internal transcribed spacer regions (ITS) in Trichomonas vaginalis isolates and differentiation among Trichomonas species

    Parasitology International, Vol. 63, Núm. 2, pp. 427-431

  4. Development of novel benznidazole formulations: Physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease

    International Journal of Pharmaceutics, Vol. 472, Núm. 1-2, pp. 110-117

  5. Further insights into biological evaluation of new anti-Trypanosoma cruzi 5-nitroindazoles

    Parasitology Research, Vol. 113, Núm. 3, pp. 1049-1056