Farmacología y Toxicología
Departamento
Instituto de Investigaciones Biomédicas Alberto Sols
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Instituto de Investigaciones Biomédicas Alberto Sols (22)
2024
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Oral anticoagulants: A plausible new treatment for Alzheimer's disease?
British Journal of Pharmacology, Vol. 181, Núm. 6, pp. 760-776
2023
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Aging, NRF2, and TAU: A Perfect Match for Neurodegeneration?
Antioxidants, Vol. 12, Núm. 8
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Beneficial effect of TLR4 blockade by a specific aptamer antagonist after acute myocardial infarction
Biomedicine and Pharmacotherapy, Vol. 158
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Sigma-1 receptor modulation fine-tunes KV1.5 channels and impacts pulmonary vascular function
Pharmacological Research, Vol. 189
2022
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IQM-PC332, a Novel DREAM Ligand with Antinociceptive Effect on Peripheral Nerve Injury-Induced Pain
International Journal of Molecular Sciences, Vol. 23, Núm. 4
2021
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KV1.3 channels are novel determinants of macrophage-dependent endothelial dysfunction in angiotensin II-induced hypertension in mice
British Journal of Pharmacology, Vol. 178, Núm. 8, pp. 1836-1854
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Molecular alterations in sporadic and sod1-als immortalized lymphocytes: Towards a personalized therapy
International Journal of Molecular Sciences, Vol. 22, Núm. 6, pp. 1-17
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Salient brain entities labelled in P2rx7-EGFP reporter mouse embryos include the septum, roof plate glial specializations and circumventricular ependymal organs
Brain Structure and Function, Vol. 226, Núm. 3, pp. 715-741
2019
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Activation of Kv7 channels as a novel mechanism for NO/cGMP-induced pulmonary vasodilation
British Journal of Pharmacology, Vol. 176, Núm. 13, pp. 2131-2145
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Identification of IQM-266, a novel DREAM ligand that modulates KV4 currents
Frontiers in Molecular Neuroscience, Vol. 12
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New flavonoid–N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 34, Núm. 1, pp. 712-727
2018
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Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 156, pp. 534-553
2016
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New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties
European Journal of Medicinal Chemistry, Vol. 121, pp. 376-386
2014
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Functional assembly of Kv7.1/Kv7.5 channels with emerging properties on vascular muscle physiology
Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 34, Núm. 7, pp. 1522-1530
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New melatonin- N, N -dibenzyl(N -methyl)amine hybrids: Potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for alzheimers disease
Journal of Medicinal Chemistry, Vol. 57, Núm. 9, pp. 3773-3785
2012
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Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity
Cell Death and Disease, Vol. 3, Núm. 1
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Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model
European Journal of Medicinal Chemistry, Vol. 47, Núm. 1, pp. 175-185
2010
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Celecoxib blocks cardiac Kv1.5, Kv4.3 and Kv7.1 (KCNQ1) channels. Effects on cardiac action potentials
Journal of Molecular and Cellular Cardiology, Vol. 49, Núm. 6, pp. 984-992
2008
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Dual-promoter lentiviral vectors for constitutive and regulated gene expression in neurons
Journal of Neuroscience Methods, Vol. 168, Núm. 1, pp. 104-112
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Excitotoxicity and focal cerebral ischemia induce truncation of the NR2A and NR2B subunits of the NMDA receptor and cleavage of the scaffolding protein PSD-95
Molecular Psychiatry, Vol. 13, Núm. 1, pp. 99-114