Publicaciones en colaboración con investigadores/as de Centro de Investigación Biomédica en Red sobre Enfermedades Hepáticas y Digestivas (26)

2023

  1. APRIL: A double-blind, placebo-controlled, randomized, Phase Ib/IIa clinical study of ApTOLL for the treatment of acute ischemic stroke

    Frontiers in Neurology, Vol. 14

  2. Academia and industry agreement on a feasibility tool for first-time-in-human clinical trial units

    Clinical and Translational Science, Vol. 16, Núm. 12, pp. 2421-2428

  3. Immune System and Brain/Intestinal Barrier Functions in Psychiatric Diseases: Is Sphingosine-1-Phosphate at the Helm?

    International Journal of Molecular Sciences, Vol. 24, Núm. 16

  4. Safety and Efficacy of ApTOLL in Patients with Ischemic Stroke Undergoing Endovascular Treatment: A Phase 1/2 Randomized Clinical Trial

    JAMA Neurology, Vol. 80, Núm. 8, pp. 779-788

  5. Saturated fatty acid-enriched small extracellular vesicles mediate a crosstalk inducing liver inflammation and hepatocyte insulin resistance

    JHEP Reports, Vol. 5, Núm. 8

2022

  1. First-in-human phase I clinical trial of a TLR4-binding DNA aptamer, ApTOLL: Safety and pharmacokinetics in healthy volunteers

    Molecular Therapy - Nucleic Acids, Vol. 28, pp. 124-135

  2. Sphk2 deletion is involved in structural abnormalities and Th17 response but does not aggravate colon inflammation induced by sub-chronic stress

    Scientific Reports, Vol. 12, Núm. 1

2021

  1. Possible unrecognised liver injury is associated with mortality in critically ill COVID-19 patients

    Therapeutic Advances in Gastroenterology, Vol. 14

2020

  1. Intestinal Epithelial Cell-Derived Extracellular Vesicles Modulate Hepatic Injury via the Gut-Liver Axis During Acute Alcohol Injury

    Frontiers in Pharmacology, Vol. 11

  2. Intraoperative Troponin Elevation in Liver Transplantation Is Independently Associated With Mortality: A Prospective Observational Study

    Liver Transplantation, Vol. 26, Núm. 5, pp. 681-692

  3. Liver–lung interactions in acute respiratory distress syndrome

    Intensive Care Medicine Experimental , Vol. 8

  4. Melatonin reduces NLRP3 inflammasome activation by increasing α7 nAChR-mediated autophagic flux

    Antioxidants, Vol. 9, Núm. 12, pp. 1-18

2017

  1. Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism

    Scientific Reports, Vol. 7

2016

  1. Early measurement of indocyanine green clearance accurately predicts short-term outcomes after liver transplantation

    Transplantation, Vol. 100, Núm. 3, pp. 613-620

2014

  1. A simple transcriptomic signature able to predict drug-induced hepatic steatosis

    Archives of Toxicology, Vol. 88, Núm. 4, pp. 967-982

2013

  1. Effects of peroxisome proliferator-activated receptor-β activation in endothelin-dependent hypertension

    Cardiovascular Research, Vol. 99, Núm. 4, pp. 622-631

  2. The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARα; And repressed by C/EBPα: Implications in FABP1 down-regulation in nonalcoholic fatty liver disease

    Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, Vol. 1831, Núm. 4, pp. 803-818

  3. Zolmitriptan: A Novel Portal Hypotensive Agent Which Synergizes with Propranolol in Lowering Portal Pressure

    PLoS ONE, Vol. 8, Núm. 1

2012

  1. Endogenous cannabinoid system regulates intestinal barrier function in vivo through cannabinoid type 1 receptor activation

    American Journal of Physiology - Gastrointestinal and Liver Physiology, Vol. 302, Núm. 5

  2. Foxa1 reduces lipid accumulation in human hepatocytes and is down-regulated in nonalcoholic fatty liver

    PLoS ONE, Vol. 7, Núm. 1