Farmacología y Toxicología
Departamento
Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (20)
2024
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Oral anticoagulants: A plausible new treatment for Alzheimer's disease?
British Journal of Pharmacology, Vol. 181, Núm. 6, pp. 760-776
2023
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Aging, NRF2, and TAU: A Perfect Match for Neurodegeneration?
Antioxidants, Vol. 12, Núm. 8
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Neutrophil β1 adrenoceptor blockade blunts stroke-associated neuroinflammation
British Journal of Pharmacology, Vol. 180, Núm. 4, pp. 459-478
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Redox Regulation of Microglial Inflammatory Response: Fine Control of NLRP3 Inflammasome through Nrf2 and NOX4
Antioxidants, Vol. 12, Núm. 9
2022
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IQM-PC332, a Novel DREAM Ligand with Antinociceptive Effect on Peripheral Nerve Injury-Induced Pain
International Journal of Molecular Sciences, Vol. 23, Núm. 4
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Multitarget Hybrid Fasudil Derivatives as a New Approach to the Potential Treatment of Amyotrophic Lateral Sclerosis
Journal of Medicinal Chemistry, Vol. 65, Núm. 3, pp. 1867-1882
2021
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Molecular alterations in sporadic and sod1-als immortalized lymphocytes: Towards a personalized therapy
International Journal of Molecular Sciences, Vol. 22, Núm. 6, pp. 1-17
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NT3/TrkC Pathway Modulates the Expression of UCP-1 and Adipocyte Size in Human and Rodent Adipose Tissue
Frontiers in Endocrinology, Vol. 12
2019
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Identification of IQM-266, a novel DREAM ligand that modulates KV4 currents
Frontiers in Molecular Neuroscience, Vol. 12
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New flavonoid–N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 34, Núm. 1, pp. 712-727
2018
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Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 156, pp. 534-553
2016
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New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties
European Journal of Medicinal Chemistry, Vol. 121, pp. 376-386
2015
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Cannabinoids in Neurodegenerative Disorders and Stroke/Brain Trauma: From Preclinical Models to Clinical Applications
Neurotherapeutics, Vol. 12, Núm. 4, pp. 793-806
2014
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New melatonin- N, N -dibenzyl(N -methyl)amine hybrids: Potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for alzheimers disease
Journal of Medicinal Chemistry, Vol. 57, Núm. 9, pp. 3773-3785
2013
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Cocaine potentiates MDMA-induced oxidative stress but not dopaminergic neurotoxicity in mice: Implications for the pathogenesis of free radical-induced neurodegenerative disorders
Psychopharmacology, Vol. 230, Núm. 1, pp. 125-135
2012
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Dopamine D 1 receptor deletion strongly reduces neurotoxic effects of methamphetamine
Neurobiology of Disease, Vol. 45, Núm. 2, pp. 810-820
2011
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Dopamine D2-receptor knockout mice are protected against dopaminergic neurotoxicity induced by methamphetamine or MDMA
Neurobiology of Disease, Vol. 42, Núm. 3, pp. 391-403
2009
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Ca2+/calmodulin-dependent kinase II signalling cascade mediates P2X7 receptor-dependent inhibition of neuritogenesis in neuroblastoma cells
FEBS Journal, Vol. 276, Núm. 18, pp. 5307-5325
2008
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Early loss of dopaminergic terminals in striosomes after MDMA administration to mice
Synapse, Vol. 62, Núm. 1, pp. 80-84
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Persistent MDMA-induced dopaminergic neurotoxicity in the striatum and substantia nigra of mice
Journal of Neurochemistry, Vol. 107, Núm. 4, pp. 1102-1112