Ciencias Químicas
Faculty
Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas
Madrid, España
2026
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Cannabinoid CB2 receptor drives trastuzumab resistance and predicts durable anti-HER2 response
Oncogene
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PCMT1 generates the C-terminal cyclic imide degron on CRBN substrates
Nature Chemical Biology, Vol. 22, Núm. 5, pp. 802-812
2025
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Contilistat, a New Multitarget Small Polyfunctionalized Indole Derivative
Synlett, Vol. 36, Núm. 16, pp. 2655-2660
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From Diarylsulfides to Diarylamines: New Ebola Virus Entry Inhibitors with Improved Metabolic Stability
Journal of Medicinal Chemistry, Vol. 68, Núm. 11, pp. 11786-11800
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Prenatal Downregulation of CB1 Cannabinoid Receptors in the Mouse Prefrontal Cortex Disrupts Cortical Lamination and Induces a Transcriptional Signature Associated with Social Interaction Deficits
The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 45, Núm. 42
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Restoration of CB1 receptor function in hippocampal GABAergic neurons rescues memory deficits in Huntington’s disease models
Translational Neurodegeneration, Vol. 14, Núm. 1
2024
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CB1 receptors in NG2 cells mediate cannabinoid-evoked functional myelin regeneration
Progress in Neurobiology, Vol. 243
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Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases
Journal of Medicinal Chemistry, Vol. 67, Núm. 18, pp. 16533-16555
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GAP43 Located on Corticostriatal Terminals Restrains Novelty-Induced Hyperactivity in Mice
Journal of Neuroscience, Vol. 44, Núm. 39
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The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls
EMBO Molecular Medicine, Vol. 16, Núm. 4, pp. 755-783
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The endocannabinoid system as a therapeutic target in neuropathic pain: a review
Expert Opinion on Therapeutic Targets, Vol. 28, Núm. 9, pp. 739-755
2023
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Control of a hippocampal recurrent excitatory circuit by cannabinoid receptor-interacting protein Gap43
Nature Communications, Vol. 14, Núm. 1
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Endocannabinoid signaling in glioma
GLIA, Vol. 71, Núm. 1, pp. 127-138
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Fatty acids fuelling astroglia and beyond
Nature Metabolism
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Identification of fatty acid amide hydrolase as a metastasis suppressor in breast cancer
Nature Communications, Vol. 14, Núm. 1
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Nanomedical research and development in Spain: improving the treatment of diseases from the nanoscale
Frontiers in Bioengineering and Biotechnology, Vol. 11
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Selective inhibition of cannabinoid CB1 receptor-evoked signalling by the interacting protein GAP43
Neuropharmacology, Vol. 240
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The GRP78-PERK axis contributes to memory and synaptic impairments in Huntington's disease R6/1 mice
Neurobiology of Disease, Vol. 184
2022
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Cannabinoid CB1 receptor gene inactivation in oligodendrocyte precursors disrupts oligodendrogenesis and myelination in mice
Cell Death and Disease, Vol. 13, Núm. 7
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Paving the Way for Reliable Alzheimer's Disease Blood Diagnosis by Quadruple Electrochemical Immunosensing
ChemElectroChem, Vol. 9, Núm. 9