Farmacia
Facultad
Antonio
García García
Publicaciones en las que colabora con Antonio García García (38)
2020
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Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties
Drug Development Research, Vol. 81, Núm. 3, pp. 283-294
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New Nrf2-inducer compound ITH12674 slows the progression of retinitis pigmentosa in the mouse model rd10
Cellular Physiology and Biochemistry, Vol. 54, Núm. 1, pp. 142-159
2017
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Addition to "ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia"
ACS chemical neuroscience, Vol. 8, Núm. 1, pp. 210
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ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia
ACS Chemical Neuroscience, Vol. 8, Núm. 1, pp. 67-81
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Novel sulfoglycolipid IG20 causes neuroprotection by activating the phase II antioxidant response in rat hippocampal slices
Neuropharmacology, Vol. 116, pp. 110-121
2015
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Melatonin-sulforaphane hybrid ITH12674 induces neuroprotection in oxidative stress conditions by a 'drug-prodrug' mechanism of action
British Journal of Pharmacology, Vol. 172, Núm. 7, pp. 1807-1821
2013
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Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia
Neuropharmacology, Vol. 67, pp. 403-411
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Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease
Medicinal Research Reviews, Vol. 33, Núm. 1, pp. 139-189
2012
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Benzothiazepine CGP37157 and its isosteric 2′-ethyl analogue provide neuroprotection and block cell calcium entry
ACS Chemical Neuroscience, Vol. 3, Núm. 7, pp. 519-529
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Galantamine elicits neuroprotection by inhibiting iNOS, NADPH oxidase and ROS in hippocampal slices stressed with anoxia/reoxygenation
Neuropharmacology, Vol. 62, Núm. 2, pp. 1082-1090
2011
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Chondroitin sulfate reduces cell death of rat hippocampal slices subjected to oxygen and glucose deprivation by inhibiting p38, NFκB and iNOS
Neurochemistry International, Vol. 58, Núm. 6, pp. 676-683
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Effects of novel tacripyrines ITH12117 and ITH12118 on rat vas deferens contractions, calcium transients and cholinesterase activity
European Journal of Pharmacology, Vol. 660, Núm. 2-3, pp. 411-419
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N-Acylaminophenothiazines: Neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 46, Núm. 6, pp. 2224-2235
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Synthesis, structure, theoretical and experimental in vitro antioxidant/pharmacological properties of α-aryl, N-alkyl nitrones, as potential agents for the treatment of cerebral ischemia
Bioorganic and Medicinal Chemistry, Vol. 19, Núm. 2, pp. 951-960
2010
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Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles
Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 16, pp. 5861-5872
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Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives
Journal of Medicinal Chemistry, Vol. 53, Núm. 14, pp. 5129-5143
2009
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Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease
Journal of Medicinal Chemistry, Vol. 52, Núm. 9, pp. 2724-2732
2008
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New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties
Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 16, pp. 7759-7769
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Synthesis of 6-amino-1,4-dihydropyridines that prevent calcium overload and neuronal death
European Journal of Medicinal Chemistry, Vol. 43, Núm. 3, pp. 668-674
2007
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An update on the pharmacology of galantamine
Expert Opinion on Investigational Drugs, Vol. 16, Núm. 12, pp. 1987-1998