Publicaciones en colaboración con investigadores/as de Instituto de Química Orgánica General (405)

2024

  1. Chitosan-based oral hydrogel formulations of β-galactosidase to improve enzyme supplementation therapy for lactose intolerance

    International Journal of Biological Macromolecules, Vol. 255

  2. Design and Synthesis of Multi-Functional Ligands through Hantzsch Reaction: Targeting Ca2+ Channels, Activating Nrf2 and Possessing Cathepsin S Inhibitory, and Antioxidant Properties

    Pharmaceutics, Vol. 16, Núm. 1

  3. Synthesis and Biological Evaluation of New Benzochromenopyrimidines for the Therapy of Colon and Lung Cancer

    ChemistrySelect, Vol. 9, Núm. 2

  4. Synthesis, antioxidant and neuroprotective analysis of diversely functionalized α-aryl-N-alkyl nitrones as potential agents for ischemic stroke therapy

    European Journal of Medicinal Chemistry, Vol. 266

2023

  1. 8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases

    Acta Pharmaceutica Sinica B, Vol. 13, Núm. 5, pp. 2152-2175

  2. Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation

    Molecules, Vol. 28, Núm. 1

  3. Design, Synthesis, in Silico and Biological Evaluation of Novel 4-Aminopyrimidine-5-carbonitriles

    ChemistrySelect, Vol. 8, Núm. 31

  4. Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer’s Disease Treatment

    International Journal of Molecular Sciences, Vol. 24, Núm. 11

  5. Fast and Sustained Axonal Growth by BDNF Released from Chitosan Microspheres

    Marine Drugs, Vol. 21, Núm. 2

2022

  1. Benzochromenopyrimidines: Synthesis, Antiproliferative Activity against Colorectal Cancer and Physicochemical Properties

    Molecules, Vol. 27, Núm. 22

  2. Evaluation of PCDD/Fs, PCBs and PBDEs in two penguin species from Antarctica

    Chemosphere, Vol. 286

  3. Improving the Efficacy of Quinolylnitrones for Ischemic Stroke Therapy, QN4 and QN15 as New Neuroprotective Agents after Oxygen–Glucose Deprivation/Reoxygenation-Induced Neuronal Injury

    Pharmaceuticals, Vol. 15, Núm. 11

  4. N-Hydroxy-N-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases

    Molecules, Vol. 27, Núm. 21

  5. Postischemic Neuroprotection of Aminoethoxydiphenyl Borate Associates Shortening of Peri-Infarct Depolarizations

    International Journal of Molecular Sciences, Vol. 23, Núm. 13

  6. Preclinical Characterization of Antioxidant Quinolyl Nitrone QN23 as a New Candidate for the Treatment of Ischemic Stroke

    Antioxidants, Vol. 11, Núm. 6

  7. Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities

    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 37, Núm. 1, pp. 2605-2620

  8. Synthesis and Pharmacological Evaluation of New N-Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout

    Journal of Medicinal Chemistry, Vol. 65, Núm. 8, pp. 6250-6260

  9. The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents

    ACS Pharmacology and Translational Science, Vol. 5, Núm. 11, pp. 1097-1108

  10. The Synthesis of 3-Nitrooxypropanol, a Methane Mitigant for Sustainable Farming with Environmental Impact: A Review

    Synthesis (Germany), Vol. 55, Núm. 14, pp. 2109-2117

2021

  1. (±)- BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease

    ACS Chemical Neuroscience, Vol. 12, Núm. 8, pp. 1328-1342