Estado de los márgenes quirúrgicos y riesgo de recidiva locorregional en cirugía conservadora del cáncer de mama¿qué distancia debe considerarse como margen afecto?

  1. SIEGRIST RIDRUEJO, JAIME RAMON
Supervised by:
  1. Elsa Mendizabal Vicente Director
  2. María Cebollero Presmanes Director
  3. Luis Ortiz Quintana Director

Defence university: Universidad Complutense de Madrid

Fecha de defensa: 26 June 2017

Committee:
  1. Felipe A. Calvo Manuel Chair
  2. J. Ruiz Rodríguez Secretary
  3. José Ignacio Sánchez Méndez Committee member
  4. Álvaro Zapico Goñi Committee member
  5. María Herrera de la Muela Committee member
Department:
  1. Salud Pública y Materno-Infantil

Type: Thesis

Teseo: 145171 DIALNET lock_openDocta Complutense editor

Abstract

AIMTo assess the effect of the distance from tumor to margin and of the involvement ofsurgical margins on the risk of locoregional recurrence (LRR).DESIGNObservational retrospective cohort study with survival analysis.KEY WORDSBreast cancer, breast conserving surgery, surgical margins, distance to margin,locoregional recurrenceBACKGROUNDFor infiltrating breast cancer, a recent meta-analysis concluded that no minimumdistance from the tumor to the margin is required in breast conserving therapy tominimize the risk of local recurrence (LR) other than no tumor on the surgicalmargin. For ductal carcinoma in situ (DCIS), another meta-analysis recommends adistance greater than 1 or 2 mm. However, several authors have questioned thesestatements due to methodological issues...