¿Existen riesgos al utilizar los concentrados de Plasma Rico en Plaquetas (PRP) de uso ambulatorio?

  1. Martínez González, JM
  2. Cano Sánchez, J
  3. Gonzalo Lafuente, JC
  4. Campo Trapero, J
  5. Esparza Gómez, GC
  6. Seoane Lestón, JM
Journal:
Medicina oral

ISSN: 1137-2834

Year of publication: 2002

Volume: 7

Issue: 5

Pages: 375-390

Type: Article

More publications in: Medicina oral

Abstract

Platelet-Rich Plasma (PRP) concentrates have been widely used in the past decade as a complement to tissue regeneration procedures. The authors who have clinically used PRP refer no risk of infection, disease transmission, or undesirable effects. Nevertheless, there have been reports on the over-expression of growth factors (GFs) and their receptors related to tumour and dysplastic tissues. This has led to evaluation of the possible coincidences between carcinogenesis and the mitogenic pathways employed by GFs. The present study provides a review of the literature on the possible effects of the therapeutic uses of GFs (including PRP) in relation to carcinogenesis, their influence upon tissues with epithelial dysplasia or oral carcinoma, and their relation to tumour growth and infiltration