Psycho-neuro-immune-endrocrine system behavior in mechanical trauma

  1. Alonso, María Soledad
  2. Arias Pérez, Jaime
  3. Aller Reyero, María Angeles
  4. López Álvarez, Laudino 1
  5. Rodríguez Fabián, Guillermo
  6. Arias Pérez, Jorge Luis 1
  7. Lorente Ruigómez, Laureano
  8. Begega Losa, Azucena 1
  9. Durán Giménez-Rico, Hipólito José
  1. 1 Universidad de Oviedo
    info

    Universidad de Oviedo

    Oviedo, España

    ROR https://ror.org/006gksa02

Revista:
Psicothema

ISSN: 0214-9915

Año de publicación: 1995

Volumen: 7

Número: 3

Páginas: 619-625

Tipo: Artículo

Otras publicaciones en: Psicothema

Resumen

Mechanical energy is an etiological factor of traumatisms which, in the human being, can produce a local pathology as well as localized systemic acute inflammation as in the case of polytraumatized patients. Acute local inflammation is a process that occurs with vasoconstriction, vasodilatation, exudation, cellular infiltration, coagulation, fibrinolysis and proliferation. These phases of the inflammation can be expressed by the endothelium, although they make up part of a localizing and successive response of the nervous, immune and endocrine systems. In the polytraumatized patients, the ischemia-revascularization, the systemic inflammatory response syndrome, the disseminated intravascular coagulation and the anabolism of the convalescence period would in turn represent the consecutive systemic expression of the nervous, immune and endocrine systems. If injury by mechanic energy produces a consecutive response of the nervous, immune and endocrine systems in the human being, it could be considered that these systems represent the successive expression of functions such as motility, digestion and proliferation which, in turn, are common components of other vital cycles existing in nature. Essentially, the final function that each system successively expresses would be a type of response that has persisted in physiological and pathological situations due to its adaptive effectivity, in this special case, to the mechanical energy.

Referencias bibliográficas

  • Ader R., Cohen N., Felten D. (1995). Psychoneuroimmunology: interactions between the nervous system and the immune system. Lancet, 345: 99-103.
  • Änggard E. (1994). Nitric oxide: mediator, murderer, and medicine. Lancet, 343: 1199-1206.
  • Barton R.N. (1985). Trauma and its metabolic problems. British Medical Bulletin, 41: 201-305.
  • Bone R.C. (1995). Sepsis, sepsis syndrome and the systemic inflammatory response syndrome (SIRS). Gulliver in Laputa. Journal of the American Medical Association, 273: 155-156.
  • Böttiger L.E. (1995). Integrative biology (physiology)- a necessity!. Journal of Internal Medicine, 237: 345-347.
  • Buja L.M., Eigenbrodt M.L., Eigenbrodt E.H. (1993). Apoptosis and necrosis. Basic types and mechanisms of cell death. Archives of Pathology and Laboratory Medicine, 117: 1208-1214.
  • Cuthbertson D.P. (1942). Post-shock metabolic response. Lancet, 1: 433-437.
  • Davies M.G., Hagen P.O. (1993). The vascular endothelium. A new horizon. Annals of Surgery, 218: 593-609.
  • Entman M.L., Smith C.W. (1994). Postreperfusion inflammation: A model for reaction to injury in cardiovascular disease. Cardiovascular Research, 28: 1301-1311.
  • Jacobs L.M., Panic S. (1994). Prehospital care: What works, What does not. Advances in Trauma and Clinical Care, 9: 1-14.
  • Kam P.C.A., Govender G. (1994). Nitric oxide: basic science and clinical applications. Anaesthesia, 49: 515-521.
  • Lewis G.P. (1978). Inflammation. Annals of the Royal College of Surgeons of England, 60: 192-198.
  • Lewis G.P. (1986). Mediators of inflammation. (pp 1-9). Bristol IOP Publishing Ltd. Wright.
  • Lum H., Malik A.B. (1994). Regulation of vascular endothelial barrier function. American Journal of Physiology, 267 (Lung Cellular Molecular Physiology, 11): L223-L241.
  • Moore E.E., Moore F.A., Franciose R.J., Kim F.J., Biffl W.L., Banerjee A. (1994). The postischemic gut serves as a priming bed for circulating neutrophils that provoke multiple organ failure. Journal of Trauma, 37: 881-887.
  • Nathan C., Xie Q.W. (1994). Nitric oxide syntheses: Roles, tolls, and controls. Cell, 78: 915-918.
  • Rangel-Frausto M.S. Pittet D., Costigan M., Hwang T., Davis C.S., Wenzel R.P. (1995). The natural history of the systemic inflammatory response syndrome (SIRS). A prospective study. Journal of the American Medical Association, 273: 117-123.
  • Shaw J.H.F., Koea J.B. (1993). Metabolic basis of the septic surgical patient. World Journal of Surgery, 17: 154-164.