Functional differences between dorsal and ventral hippocampus revealed with agnor staining .
- González Pardo, Héctor 1
- García Moreno, Luis Miguel
- Arias Pérez, Jorge Luis 1
- Cimadevilla Redondo, José Manuel 1
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1
Universidad de Oviedo
info
ISSN: 0214-9915
Ano de publicación: 2000
Volume: 12
Número: 2
Páxinas: 293-295
Tipo: Artigo
Outras publicacións en: Psicothema
Resumo
Recientemente se han encontrado diferencias en cuanto a la actividad neural de la formación hipocámpica en sus zonas dorsal y ventral. Estas diferencias podrían jugar un importante papel en cuanto a la implicación diferencial de estas zonas en el aprendizaje y la memoria. Aplicamos aquí la técnica histológica de impregnación argéntica de las regiones organizadoras del nucleolo (AgNORs) con el fin de analizar la actividad biosintética de las areas hipocampales CA1 y CA3 en las zonas dorsal y ventral de ratas Wistar. Se cuantificaron el número y área media de los AgNORs presentes en sus neuronas, que son indicadores indirectos de la actividad de síntesis proteica. Los resultados muestran una actividad biosintética significativamente mayor en la región dorsal de ambas áreas estudiadas, que concuerda con estudios anteriores y se discuten sus implicaciones funcionales.
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