Determination of ceftizoxime hydrolysis constants reaction by high pressure liquid chromatography

  1. Doadrio Villarejo, Antonio Luis
  2. Orenga, Regina
Zeitschrift:
Anales de la Real Academia Nacional de Farmacia

ISSN: 1697-4298 0034-0618

Datum der Publikation: 2000

Nummer: 2

Seiten: 3

Art: Artikel

Andere Publikationen in: Anales de la Real Academia Nacional de Farmacia

Zusammenfassung

In this paper, we have carried out the determination of ceftizoxime constants reaction by liquid chromatography at a pH range of 2-8 and temperatures of 30-60ºC. From the study of chromatographic profiles and U.V. spectra of the eluted fractions, it is possible to propose the reaction mechanism consider in the assay conditions.