Manifestaciones retinianas secundarias a hiperhomocisteinemia en un caso de alcoholismo crónico
- Palmero-Fernández, L.
- Fernández-Tresguerres, F.
- Santos Bueso, Enrique
- Sáenz Francés, Federico
- Martínez de la Casa, José M.
- García Feijoo, Julián
- García Sánchez, Julián
ISSN: 0365-6691
Année de publication: 2014
Volumen: 89
Número: 8
Pages: 336-339
Type: Article
D'autres publications dans: Archivos de la Sociedad Española de Oftalmologia
Résumé
Case report An alcoholic patient with loss of vision in his right eye and a peripapillar haemorrhage, who then presented with a venous thrombosis. Blood analysis revealed hyperhomocysteinemia with coagulation parameters within the normal range. In the follow-up he developed a bilateral optic neuropathy. Discussion An increase in homocysteine levels is common in alcoholics, and it has been considered a vascular risk factor. Folic acid and vitamins B₆ and B₁₂ deficiency may lead to hyperhomocysteinemia, as they participate in its metabolism. Conclusions When presented with a retinal occlusive disease or ischemic optic neuropathy in young patients, coagulation disorders and elevated levels of homocysteine should be ruled out.