Cambios en la actividad cerebral en el envejecimiento normal en una tarea con interferencia valorados mediante magnetoencefalografía
- Elena Solesio Jofre de Villegas
- Fernando Maestú Unturbe
- P. Campo
- A. Capilla
- B. Mangas
- J. González
- T. Ortiz
ISSN: 1888-6116
Year of publication: 2008
Volume: 19
Issue: 3
Pages: 178-182
Type: Article
More publications in: Trauma
Abstract
Objective: To determine whether performing a recognition task under interference conditions produces changes in brain activity pattern compared with the activity seen under conditions of passive interference. Population and methods: Twenty healthy elderly subjects were subjected to magnetoencephalography. In each patient we applied the Wechsler Memory Scale-III (WMS-III), the Wechsler Intelligence Scale, the Boston Naming Test, the verbal fluency test, the Wisconsin card classification test, the Trail Making Test and the colors and words test (STROOP). The recordings were made using a 148-channel magnetoencephalograph capable of measuring the magnetic activity generated within the entire cranial convexity. Results: Greater activation was recorded under active interference conditions in the medial temporal regions, visual cortex and anterior ventral area in the first 400 ms in the left hemisphere and only in the right hemisphere for the visual cortex, while under passive interference conditions, increased activation was obtained in the anterior ventral region during the 700-800 ms in the left hemisphere. Conclusion: The presentation of both types of interference, active and passive, modulates the fronto-temporal activation patterns in normal aging.