Terapia de inicio con infliximab en una vasculitis oclusiva bilateral como inicio de una enfermedad de Behçet

  1. P. Bañeros-Rojas
  2. C. Berrozpe-Villabona
  3. J.E. Peraza-Nieves
  4. D. Díaz-Valle 1
  1. 1 Universidad Complutense de Madrid 920415-GR58/08, Madrid, España (Grupo de investigacion)
Journal:
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Year of publication: 2015

Volume: 90

Issue: 6

Pages: 285-288

Type: Article

DOI: 10.1016/J.OFTAL.2014.03.016 DIALNET GOOGLE SCHOLAR

More publications in: Archivos de la Sociedad Española de Oftalmologia

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Abstract

Case report A 24 year old woman who complained of maculo-papulo rash, genital and bucal aphthous ulcers, abdominal pain, minor dyspnea and visual loss in both eyes. Funduscopy revealed a bilateral occlusive vasculitis including central vessels. Treatment was initiated with a methylprednisolone bolus (1 g/24 h) and infliximab 5 mg/kg/day (0-2-6 weeks and every 8 weeks). The treatment prescribed induced a fast remission. Visual acuity improved. The patient did not suffer any other relapse after one year of follow-up. Discussion An initial treatment with Infliximab should be considered in Behçet disease for serious outbreaks, such as macular occlusive vasculitis with ischemia.