Propuesta de un procedimiento de validación de un método para la determinación de cinc sérico: cumplimiento de los requisitos de la ISO 17025

  1. M.T. Llorente Ballesteros 1
  2. I. Navarro Serrano 1
  3. J.L. López Colón 1
  1. 1 Instituto de Toxicología de la Defensa, Madrid, España
Journal:
Revista de calidad asistencial

ISSN: 1134-282X

Year of publication: 2015

Volume: 30

Issue: 6

Pages: 319-326

Type: Article

DOI: 10.1016/J.CALI.2015.08.001 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Revista de calidad asistencial

Abstract

Objective The aim of this report is to propose a scheme for validation of an analytical technique according to ISO 17025. Material and methods According to ISO 17025, the fundamental parameters tested were: selectivity, calibration model, precision, accuracy, uncertainty of measurement, and analytical interference. Results A protocol has been developed that has been applied successfully to quantify zinc in serum by atomic absorption spectrometry. Conclusion It is demonstrated that our method is selective, linear, accurate, and precise, making it suitable for use in routine diagnostics.

Data source: Dialnet