Histiocitosis de células de Langerhans con manifestaciones multisistémicas en periodo neonatal

  1. Días-Castro, Rosalba
  2. Martínez, Gloria
  3. Cruz, Claudia Elena
  4. Meza, Ivonne
  5. Ruiz, Germán
  6. Ortíz, Alex
  7. Pasaje, Donaldo
Journal:
Revista Facultad Ciencias de la Salud: Universidad del Cauca

ISSN: 2538-9971,  0124-308X

Year of publication: 2011

Issue Title: Revista Facultad Ciencias de la Salud, Universidad del Cauca

Volume: 13

Issue: 2

Pages: 15-19

Type: Article

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Abstract

We report an unusual case of mediastinal abcessed mass, with involvement of the lung, thymus and probably bone and hematopoietic system, in a newborn that was diagnosed with Langerhans cell histiocytosis. Its interest lies in the presentation as a rare cause of medias­tinal mass with involvement of other organs. Histologic exa­mination of the surgical specimen demonstrated Langerhans cell histiocytosis. It is known that vascular and lymphatic malformations, with teratomas, neurogenic tumors, lympha­denopathy of infectious origin and mediastinitis, are a major cause of mediastinal masses; in this case, it must also take into account the Langerhans Cell Histiocytosis as a cause. It had already reported cases of congenital solid masses neck and thigh as a unique presentation of this disease.

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