Valoración clínica intraoperatoria de la infusión continua de fentanilo-lidocaína-ketamina (FLK) en perrosestudio retrospectivo

  1. N. Chitro
  2. E. Barderas
  3. J. Benito de la Vívora
  4. Rafael Cediel Algovia
  5. Ignacio Álvarez Gómez De Segura
  6. S. Canfrán
Journal:
Clínica veterinaria de pequeños animales: revista oficial de AVEPA, Asociación Veterinaria Española de Especialistas en Pequeños Animales

ISSN: 1130-7064

Year of publication: 2016

Volume: 36

Issue: 4

Pages: 275-283

Type: Article

More publications in: Clínica veterinaria de pequeños animales: revista oficial de AVEPA, Asociación Veterinaria Española de Especialistas en Pequeños Animales

Abstract

The aim of this case-control retrospective study (2006-2013) was to determine whether inhalational anaesthetic requirements were reduced in patients receiving fentanyl-lidocaine-ketamine (FLK) intraoperatively compared to those who did not receive this infusion. The FLK protocol used was fentanyl (4.5 μg/kg/h), ketamine (0.6 mg/kg/h) and lidocaine (3 mg/kg/h), with a previous loading dose. A total of 88 dogs (cases) receiving FLK categorized by type of surgery, and 78 dogs (controls) undergoing the same surgical procedures but not receiving FLK were included. Sevoflurane or isoflurane were used to maintain anaesthesia. For the comparative study, the doses of anaesthetic were considered in relation with the minimum alveolar concentration (MAC) of the dog, so both inhalation anaesthetics could be compared together in the same study. Both demographics and the anaesthetic protocol used were considered for the descriptive and comparative analysis. The FLK and control groups were compared using the Student’s t-test (parametric data) and Mann-Whitney U test (non-parametric data). FLK administration produced a significant reduction (21 %) of the inhalational agent requirements in all surgeries, without differences between them. In conclusion, inhaled anaesthetic requirements for maintenance are significantly reduced when FLK is included in the anaesthetic protocol, regardless of the type of surgical procedure.