Oral tongue cancer in public hospitals in Madrid, Spain (1990-2008)

  1. Ana Isabel García Kass 1
  2. Alicia Herrero Sánchez 1
  3. G. Esparza Gómez 2
  1. 1 DDS, PhD, Department of Oral Medicine and Orofacial Surgery, School of Dentistry, Complutense University of Madrid
  2. 2 MS, DDS, PhD, Professor in the Department of Oral Medicine and Orofacial Surgery, School of Dentistry, Complutense University of Madrid
Revista:
Medicina oral, patología oral y cirugía bucal. Ed. inglesa

ISSN: 1698-6946

Año de publicación: 2016

Volumen: 21

Número: 6

Páginas: 1

Tipo: Artículo

DOI: 10.4317/MEDORAL.21196 DIALNET GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Medicina oral, patología oral y cirugía bucal. Ed. inglesa

Resumen

The cancer which appears in the mobile portion of the tongue is the most common neoplasm of the oral cavity. The objective of this study was to analyse oral tongue cancer epidemiology in a population of 610 patients diagnosed between 1990 and 2008 and detailed in the Tumour Registry of the Madrid region. A retrospective analysis based on the following variables provided in the Tumour Registry was achieved: age, gender, histology, stage, location, treatment. Descriptive and analytic statistics with these variables, using Pearson’s Chi-square test to study the relationship between the qualitative variables. Patients’ mean age was 61.53±13.95 years, with a gender ratio of 2.09:1 (413 males vs 197 females). The lesion was mainly localized in the lateral border of tongue, with other sites (dorsal face, ventral face, lingual tonsil, contiguous sites, tongue NOS) represented at lower rates. Squamous cell carcinomas (94.9%) far outweighted other histologies (salivary gland tumours, soft tissue tumours, haematolymphoid tumours). 59% of the cases appeared in localized stages, versus 35.2% in regional and 4.8% in distant stages. Surgery was the most frequently used treatment, followed by surgery in combination with radiotherapy. Oral tongue cancer is a disease of the elderly, with a male predominance. It mainly appears in its lateral border, localized squamous cell carcinomas representing the great majority of lingual neoplasms.

Referencias bibliográficas

  • Llewelyn, J, Mitchell, R. (1994). Smoking, alcohol and oral cancer in south east Scotland: a 10-year experience. Br J Oral Maxillofac Surg. 32. 146
  • Ho, PS, Ko, YC, Yang, YH, Shieh, TY, Tsai, CC. (2002). The incidence of oropharyngeal cancer in Taiwan: an endemic betel quid chewing area. J Oral Pathol Med. 31. 213
  • Coleman, MP, Gatta, G, Verdecchia, A, Estève, J, Sant, M, Storm, H. (2003). EUROCARE-3 summary: cancer survival in Europe at the end of the 20th century. Ann Oncol. 145. 128
  • Alho, OP, Kantola, S, Pirkola, U, Laara, E, Jokinen, K, Pukkala, E. (1999). Cancer of the mobile tongue in Finland--increasing incidence, but improved survival. Acta Oncol. 38. 1021
  • Kantola, S, Parikka, M, Jokinen, K, Hyrynkangs, K, Soini, Y, Alho, OP. (2000). Prognostic factors in tongue cancer - relative importance of demographic, clinical and histopathological factors. Br J Cancer. 83. 614
  • Herranz Gonzalez-Botas, J, Vazquez Barro, C, Lopez Amado, M, Martinez Moran, A, Chao Vieites, J. (2002). Factors affecting local and regional control and survival of carcinomas of the tongue and floor of mouth. Acta Otorrinolaringol Esp. 53. 32
  • Haddadin, KJ, Soutar, DS, Webster, MH, Robertson, AG, Oliver, RJ, MacDonald, DG. (2000). Natural history and patterns of recurrence of tongue tumours. Br J Plast Surg. 53. 279
  • Gorsky, M, Epstein, JB, Oakley, C, Le, ND, Hay, J, Stevenson-Moore, P. (2004). Carcinoma of the tongue: a case series analysis of clinical presentation, risk factors, staging, and outcome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 98. 546
  • Rao, DN, Shroff, PD, Chattopadhyay, G, Dinshaw, KA. (1998). Survival analysis of 5595 head and neck cancers--results of conventional treatment in a high-risk population. Br J Cancer. 77. 1514
  • Macfarlane, GJ, Boyle, P, Scully, C. (1987). Rising mortality from cancer of the tongue in young Scottish males. Lancet. 28564. 912
  • Davis, S, Severson, RK. (1987). Increasing incidence of cancer of the tongue in the United States among young adults. Lancet. 28564. 910
  • Macfarlane, GJ, Boyle, P, Evstifeeva, TV, Robertson, C, Scully, C. (1994). Rising trends of oral cancer mortality among males worldwide: the return of an old public health problem. Cancer Causes Control. 5. 259
  • Shiboski, CH, Schmidt, BL, Jordan, RC. (2005). Tongue and tonsil carcinoma: increasing trends in the U.S. population ages 20-44 years. Cancer. 103. 1843
  • Mackenzie, J, Ah-See, K, Thakker, N, Sloan, P, Maran, AG, Birch, J. (2000). Increasing incidence of oral cancer amongst young persons: what is the aetiology? Oral Oncol. 36. 387
  • Santos-Silva, AR, Ribeiro, AC, Soubhia, AM, Miyahara, GI, Carlos, R, Speight, PM. (2011). High incidences of DNA ploidy abnormalities in tongue squamous cell carcinoma of young patients: an international collaborative study. Histopathology. 58. 1127
  • Atula, S, Grenman, R, Laippala, P, Syrjanen, S. (1996). Cancer of the tongue in patients younger than 40 years. A distinct entity? Arch Otolaryngol Head Neck Surg. 122. 1313
  • Duroux, S, Michelet, V, Majoufre, C, Siberchicot, F, Pinsolle, J. (1996). Carcinoma of the oral cavity in adults less than 30 years of age. Rev Stomatol Chir Maxillofac. 97. 225
  • Izarzugaza, MI, Esparza, H, Aguirre, JM. (2001). Epidemiological aspects of oral and pharyngeal cancers in the Basque Country. J Oral Pathol Med. 30. 521
  • Yeole, BB, Sankaranarayanan, R, Sunny, MScL, Swaminathan, R, Parkin, DM. (2000). Survival from head and neck cancer in Mumbai (Bombay), India. Cancer. 89. 437
  • Garavello, W, Spreafico, R, Gaini, RM. (2007). Oral tongue cancer in young patients: a matched analysis. Oral Oncol. 43. 894
  • Manuel, S, Raghavan, SK, Pandey, M, Sebastian, P. (2003). Survival in patients under 45 years with squamous cell carcinoma of the oral tongue. Int J Oral Maxillofac Surg. 32. 167
  • Iype, EM, Pandey, M, Mathew, A, Thomas, G, Sebastian, P, Nair, MK. (2001). Oral cancer among patients under the age of 35 years. J Postgrad Med. 47. 171