Hipofosfatasia y talasemia minor, una asociación poco frecuenteconsideraciones odontológicas sobre un caso clínico
- Noelia Caño Gómez
- Natalia Martínez Rodríguez
- Sandra Martínez González
- Joaquín De Nova García
- José Mª Martínez González
ISSN: 1697-6398, 1697-641X
Year of publication: 2016
Volume: 13
Issue: 3
Pages: 29-34
Type: Article
More publications in: Científica dental: Revista científica de formación continuada
Abstract
Introduction: The hypophospatasia is a rare inherited disorder characterized by a defect in the mineralization of bone and teeth and a decrease in serum alkaline phosphatase that causes anormal bone mineralization, premature exfoliation of teeth and severe bone atrophy. While the thalassemia are a group of inherited anemias characterized by decreased synthesis of polypeptide chains of hemoglobin that course with late puberal development , brittle bones, heart failure and anemia. The purpose of this publication is to present a case with the association of both diseases and to evaluate its dental management. Case Report: a case report of a 55 year old woman referred by stability problems in the lower denture. The patient has been diagnosed in adult form of hypophosphatasia and β-thalassemia minor. She refers having been subjected to a caesarean and six surgical interventions for bone fractures. After assessing the different therapeutic options and having obtained the informed consent from the patient, her lower overdenture was adapted adding two locators. Conclusions: hypophosphatasia is a rare disease that should be in the knowledge of the professionals of the oral health.