Lupus eritematoso sistémico (I). Etiopatogenia. Manifestaciones clínicas. Historia natural. Pruebas diagnósticas. Diagnóstico diferencial

  1. Galindo, M.
  2. Molina, R.A.
  3. Álvarez, J.L. Pablos
Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Año de publicación: 2017

Título del ejemplar: Enfermedades del sistema inmune y reumatológicas (II) Lupus eritematoso. Esclerodermia. Enfermedad mixta del tejido correctivo

Serie: 12

Número: 25

Páginas: 1429-1439

Tipo: Artículo

DOI: 10.1016/J.MED.2017.01.001 DIALNET GOOGLE SCHOLAR

Otras publicaciones en: Medicine: Programa de Formación Médica Continuada Acreditado

Objetivos de desarrollo sostenible

Resumen

Concept and epidemiology Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder of unknown unknown aetiology affecting predominantly women between their second and fifth decades of life. Etiopathogenesis Its aetiology involves genetic as well as hormonal and environmental factors, notable amongst those are some infections, particularly viral ones, and the exposure to ultraviolet light or certain drugs. Clinical manifestations The clinical spectrum is very broad, with skin and mucous, hematological and joint manifestations as well as lupus nephritis being the most common. Comorbidities The risk of developing comorbidities like infections, arteriosclerosis, osteoporosis and certain neoplasms is increased as a consequence of the disease itself and of the treatments used for controlling it. Diagnosis Diagnosis of SLE is conducted by gathering clinical data and lab tests, after ruling out possible differential diagnoses of the disease.

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