Biomarcadores salivales en patología de estrés
- Luis Miguel Sáez Alcaide
- Víctor Manuel Paredes Rodríguez
- Paula Ochoa García-Seisdedos
- José González Serrano
- Juan López-Quiles Martínez
- Gonzalo Hernández Vallejo
ISSN: 1697-6398, 1697-641X
Year of publication: 2016
Volume: 13
Issue: 2
Pages: 49-53
Type: Article
More publications in: Científica dental: Revista científica de formación continuada
Abstract
Saliva is an organic fluid composed of 99% of water and 1% of organic and inorganic components and it has taken importance on diagnosis of some pathologies because of the information it provides, being an accessible, cheap and non-invasive tool. Stress has been described as a cause of prevalent pathologies of our society such as anxiety or depression. It has been observed that high levels of stress involves an increase in blood and in saliva of substances that can be quantitative measured, commonly known as biomarkers. Thus, the aim of this review is to summarize the most useful salivary biomarkers in diagnosis and follow-up of stressed patients. In spite of being necessary more studies to clarify the true relation between salivary biomarkers and stress, it has been observed that substances such as cortisol, α-amylase, chromogranin A and secretory immunoglobulin A are useful not only alone but also mixed in diagnosis and follow-up of stressed patients, being a direct relation between stress exposure and changes in levels of this biomarkers.