Risk factors associated with xerostomia in haemodialysis patients

  1. Rosa Mª López-Pintor Muñoz 1
  2. Lucía López Pintor 2
  3. Elisabeth Casañas Gil 3
  4. Lorenzo Arriba de la Fuente 4
  5. Gonzalo Hernández Vallejo 5
  1. 1 DDS,PhD, Assistant Professor. Department of Oral Medicine and Surgery, School of Dentistry, Complutense University, Madrid, Spain
  2. 2 Nursing graduate. Haemodialysis Clinic Asyter, Alcázar de San Juan, Spain
  3. 3 DDS,PhD, student. Oral Medicine postgraduate, Department of Oral Medicine and Surgery, School of Dentistry, Complutense University, Madrid, Spain
  4. 4 MD,DDS,PhD, Assistant Professor. Department of Oral Medicine and Surgery, School of Dentistry, Complutense University, Madrid, Spain
  5. 5 MD,DDS,PhD, Professor. Department of Oral Medicine and Surgery, School of Dentistry, Complutense University, Madrid, Spain
Revista:
Medicina oral, patología oral y cirugía bucal. Ed. inglesa

ISSN: 1698-6946

Año de publicación: 2017

Volumen: 22

Número: 2

Páginas: 7

Tipo: Artículo

DOI: 10.4317/MEDORAL.21612 DIALNET GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Medicina oral, patología oral y cirugía bucal. Ed. inglesa

Resumen

To determine the prevalence of xerostomia and hyposalivation in Haemodialysis (HD) patients, to clarify risk factors, assess patient´s quality of life, and to establish a possible correlation among interdialytic weight gain (IDWG) and xerostomia. This study was performed on a group of 50 HD patients. Data were collected using a questionnaire containing demographic and clinical variables, a visual analogue scale (VAS) for xerostomia, IDWG, and an oral health impact profile questionnaire (OHIP-14). Unstimulated whole saliva (UWS) and stimulated whole saliva (SWS) were collected. A total of 28 HD patients (56%) suffered xerostomia. Dry mouth was associated with hypertension (OR, 5.24; 95% CI, 1.11-24.89) and benzodiazepine consumption (OR, 5.96; 95% CI, 1.05-33.99). The mean xerostomia VAS and OHIP-14 scores were 31.74±14.88 and 24.38±11.98, respectively. No significant correlation was observed between IDWG% and VAS and OHIP total score. Nonetheless, a positive correlation between VAS level of thirst and IDWG% was found (r=0.48 p=0.0001). UWS and SWS means (determined in 30 patients) were 0.16±0.17 and 1.12±0.64, respectively. Decreased values of UWS and SWS were reported in 53.33% and 36.66% of HD patients. Xerostomia in HD has a multifactorial aetiology due to accumulative risks as advanced age, systemic disorders, drugs, fluid intake restriction, and salivary parenchymal fibrosis and atrophy. Therefore, it is important to detect possible xerostomia risk factors to treat correctly dry mouth in HD patients and avoid systemic complications.

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