Reducción de la permeabilidad corneal en pacientes tratados con HP-Guarestudio fluorofotométrico

  1. I. Cerván-López
  2. F. Sáenz-Francés-San-Baldomero
  3. J.M. Benítez-Del-Castillo
  4. J. García-Sánchez
Revista:
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Ano de publicación: 2006

Volume: 81

Número: 6

Páxinas: 327-332

Tipo: Artigo

DOI: 10.4321/S0365-66912006000600006 DIALNET GOOGLE SCHOLAR lock_openAcceso aberto editor

Outras publicacións en: Archivos de la Sociedad Española de Oftalmologia

Resumo

Introduction: The incidence of dry eye disease, which mainly affects the corneal epithelium, is rising. The main treatment is still the use of artificial tears capable of improving the humidification and lubrication of the corneal epithelium, and avoiding its progressive functional failure. HP-Guar is a new compound used for this purpose. Methods: We performed a prospective, masked and paired study on the left eye of 10 patients suffering from dry eye disease. Corneal permeability measurements were performed by fluorophotometry after instilling 40 µL of a solution of 2% sodium fluorescein, before and after treatment with the HP-Guar drops. The results were analysed using Wilcoxon test for paired data. Results: A mean decrease in corneal permeability of 45%, after the use of HP-Guar drops was found (p=0.002). Conclusions: HP-Guar provides a new therapeutic option significantly decreasing corneal epithelial permeability.

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Fonte de datos: Dialnet