New horizons in anticoagulationdirect oral anticoagulants and their implications in oral surgery
- Víctor Serrano Sánchez 1
- Jorge Ripollés de Ramón 2
- L. Collado Yurrita 3
- Iris Vaello Checa 1
- Constantino Colmenero Ruiz 4
- Alexandra Helm 5
- María José Ciudad Cabañas 6
- Victoriano Serrano Cuenca 7
- 1 DDS. Collaborator in the Department of Medicine at the Faculty of Medicine. Faculty of Dentistry of Complutense University of Madrid
- 2 DDS, PhD. Collaborator in Departament of Oral Medicine & Orofacial Surgery. Faculty of Dentistry of Complutense University of Madrid. Collaborate Professor at the Master of Oral Surgery and Implantology UC
- 3 Director of the Department of Medicine. Faculty of Medicine of Complutense University of Madrid
- 4 DDS. Faculty of Dentistry of Complutense University of Madrid. Collaborator in the Master in Oral Surgery at the University Hospital of Príncipe de Asturias (UAH)
- 5 DDS. Faculty of Dentistry of Complutense University of Madrid
- 6 Department of Medicine. Faculty of Medicine of Complutense University of Madrid
- 7 MD, DDS, PHD. Professor of Departament of Oral Medicine & Orofacial Surgery. Faculty of Dentistry of Complutense University of Madrid
ISSN: 1698-6946
Año de publicación: 2017
Volumen: 22
Número: 5
Páginas: 12
Tipo: Artículo
Otras publicaciones en: Medicina oral, patología oral y cirugía bucal. Ed. inglesa
Resumen
Thrombotic disorders remain a leading cause of death in the Western World. For decades, vitamin K antagonists used in the prevention of this pathology, such as warfarin or sintrom, were the only oral agents available for long-term anticoagulation, in spite of their disadvantages. An electronic database search was carried out on MedLine and The Cochrane Library Plus, without restrictions on the type of study nor dates, in English and Spanish. Abstracts were reviewed, and complete articles if necessary, considering all articles that included recommendations on DOACs and oral surgery. In recent years, the so-called “new oral anticoagulants” have been introduced in clinical practice to treat those patients whose medical conditions require long-term anticoagulant treatment, replacing traditional oral anticoagulants. The new oral anticoagulants represent new therapeutic options, with a number of advantages such as poor interaction with food, minor drug interactions, and do not require periodic dose adjustments or routine controls. The purpose of this review is to establish an update on the new oral anticoagulants: Dabigatran, Rivarozaban, Apixaban and Edoxaban.
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