Oral lesions in Sjögren’s syndromea systematic review

  1. Julia Serrano 1
  2. Rosa Mª López-Pintor Muñoz 1
  3. José González Serrano 1
  4. Mónica Fernández Castro 2
  5. Elisabeth Casañas Gil 1
  6. Gonzalo Hernández Vallejo 1
  1. 1 Department of Oral Medicine and Surgery, School of Dentistry, Complutense University, Madrid, Spain
  2. 2 Rheumatology Service, Hospital Infanta Sofía, Madrid, Spain
Revista:
Medicina oral, patología oral y cirugía bucal. Ed. inglesa

ISSN: 1698-6946

Año de publicación: 2018

Volumen: 23

Número: 4

Páginas: 4

Tipo: Artículo

DOI: 10.4317/MEDORAL.22286 DIALNET GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Medicina oral, patología oral y cirugía bucal. Ed. inglesa

Resumen

Sjögren’s syndrome (SS) is an autoimmune disease related to two common symptoms: dry mouth and eyes. Although, xerostomia and hyposialia have been frequently reported in these patients, not many studies have evaluated other oral manifestations. The aim of this systematic review was to investigate prevalence rates of oral lesions (OL) in SS patients and to compare it to a control group (CG), when available. An exhaustive search of the published literature of the Pubmed, Scopus, Web of Science and the Cochrane Library databases was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) for relevant studies that met our eligibility criteria (up to September 1st 2017). Seventeen cross-sectional studies and one cohort study were finally included. The results showed that SS patients presented more OL compared to non-SS patients. The most frequent types of OL registered in primary and secondary SS were angular cheilitis, atrophic glossitis, recurrent oral ulcerations and grooves or fissurations of the tongue, also when compared to a CG. OL are common and more frequent in SS patients when compared to a CG. This may be a consequence of low levels of saliva. More studies where these OL and all the possible cofounding factors are taken into account are needed.

Referencias bibliográficas

  • Aframian, DJ,Konttinen, YT,Carrozzo, M,Tzioufas, A. (2013). Urban legends series: Sjögren's syndrome. Oral Dis. 19. 46-58
  • Mathews, SA,Kurien, BT,Scofield, R. (2008). Oral manifestations of Sjögren's syndrome. J Dent Res. 87. 308
  • Blochowiak, K,Olewicz-Gawlik, A,Polanska, A,Nowak-Gabryel, M,Kocięcki, J,Witmanowski, . (2016). Oral mucosal manifestations in primary and secondary Sjögren syndrome and dry mouth syndrome. Adv Dermatol Allergol. 33. 23
  • Baldini, C,Talarico, R,Tzioufas, AG,Bombardieri, . (2012). Classification criteria for Sjogren's syndrome: A critical review. J Autoimmun. 19. 9-14
  • Patel, R,Shahane, . (2014). The epidemiology of Sjögren's syndrome. Clin Epidemiol. 6. 247
  • Vitali, C,Bombardieri, S,Jonsson, R,Moutsopoulos, HM,Alexander, EL,Carsons, S. (2002). Classification criteria for Sjogren's syndrome: a revised version for the European criteria proposed by the American-European Consensus Group. ARD. 61. 554
  • Shiboski, CH,Shiboski, SC,Seror, R,Criswell, LA,Labetoulle, M,Lietman, T. (2016). 2016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjögren's syndrome. A consensus and data-driven methodology involving three international patient cohorts. ARD. 76. 9-16
  • Ship, JA,Fox, PC,Baum, B. (1991). How much saliva is enough? 'Normal' function defined. JADA. 122. 63
  • Márton, K,Boros, I,Varga, G,Zelles, T,Fejérdy, P,Zeher, . (2006). Evaluation of palatal flow rate and oral manifestations in patients with Sjögren's syndrome. Oral Dis. 12. 480
  • Sciubba, J. (1994). Sjögren's syndrome: pathology, oral presentation, and dental management. Compendium. 15. 1084
  • Lundström, IM,Lindström, F. (1995). Subjective and clinical oral symptoms in patients with primary Sjögren's syndrome. Clin Exp Rheumatol. 13. 725
  • Koseki, M,Maki, Y,Matsukubo, T,Ohashi, Y,Tsubota, . (2004). Salivary flow and its relationship to oral signs and symptoms in patients with dry eyes. Oral Dis. 10. 75-80
  • Fox, PC,Bowmann, SJ,Segal, B,Vivino, FB,Murukutla, N,Choueiri, . (2008). Oral involvement in primary Sjögren syndrome. JADA. 139. 1592
  • Soto-Rojas, A,Villa, A,Sifuentes-Osornio, J,Alarcón-Segovia, D,Kraus, . (1998). Oral manifestations in patients with Sjögren's syndrome. J Rheum. 25. 906
  • Likar-Manookin, K,Stewart, C,Al-Hashimi, I,Curtis, W,Berg, K,Cherian, . (2013). Prevalence of oral lesions of autoimmune etiology in patients with primary Sjogren's syndrome. Oral Dis. 19. 598-603
  • Shamseer, L,Moher, D,Clarke, . (2015). Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ. 349. 7647
  • Munn, Z,Moola, S,Riitano, D,Lisy, . (2014). The development of a critical appraisal tool for use in systematic reviews addressing questions of prevalence. IJHPM. 3. 123
  • Soto-Rojas, A,Villa, A,Sifuentes-Osornio, J,Alarcón-Segovia, D,Kraus, . (1998). Oral candidiasis and Sjögren's syndrome. J Rheum. 25. 911
  • Rhodus, NL,Bloomquist, C,Liljemark, W,Bereuter, . (1997). Prevalence, density, and manifestations of oral Candida albicans in patients with Sjögren's syndrome. J Otolaryngol. 26. 300
  • Rhodus, NL,Bloomquist, C,Liljemark, W,Bereuter, . (1999). Oral Candida albicans in patients with Sjögren's syndrome. ENT Journal. 78. 47-53
  • Tapper-Jones, L,Aldred, M,Walker, D. (1980). Prevalence and intraoral distribution of Candida albicans in Sjögren's syndrome. J Clin Pathol. 33. 282
  • MacFarlane, T. (1984). The oral ecology of patients with severe Sjögren's syndrome. Microbios. 41. 99-106
  • Hernández, YL,Daniels, T. (1989). Oral candidiasis in Sjögren's syndrome: prevalence, clinical correlations, and treatment. Oral Surg Oral Med Oral Pathol. 68. 324
  • Kindelan, SA,Yeoman, CM,Douglas, CWI,Franklin, . (1998). A comparision of intraoral Candida carriage in Sjögren's syndrome patients with healthy xerostomic controls. Oral Surg Oral Med Oral Pathol. 85. 162
  • Pedersen, AM,Reibel, J,Nordgarden, H,Bergem, HO,Jensen, JL,Nauntofte, . (1999). Primary Sjögren's syndrome: salivary gland function and clinical oral findings. Oral Dis. 5. 128
  • Patinen, P,Aine, L,Collin, P,Hietanen, J,Korpela, M,Enckell, . (2004). Oral findings in coeliac and Sjögren's syndrome. Oral Dis. 10. 330
  • McMillan, AS,Leung, KW,Wong, MCM,Lau, CS,Mok, TM. (2004). Oral health condition and saliva flow in southern Chinese with Sjögren's syndrome. Int Dent J. 54. 159
  • Ergun, S,Cekici, A,Nursen Topcuoglu, N,Migliari, DA,Güven Külekçi, G,Tanyeri, . (2010). Oral status and Candida colonization in patients with Sjögren's Syndrome. Med Oral Patol Oral Cir Bucal. 15. 310
  • Yan, Z,Young, LA,Hua, H,Xu, . (2011). Multiple Oral Candida Infections in Patients with Sjögren's syndrome- Prevalence and Clinical and Drug Susceptibility Profiles. J Rheum. 38. 2428
  • Olate, S,Muñoz, D,Neumann, S,Pozzer, L,Cavalieri-Pereira, L,de Moraes, . (2014). A descriptive study of the oral status in subjects with Sjögren's syndrome. IJCEM. 7. 1140