Seguimiento clínico del ensayo de una vacuna VLP para los serotipos 1 y 1+4 de la lengua azul en ganado ovino

  1. Ana Cristina Pérez de Diego 1
  2. Pablo del Carmen 1
  3. Javier Carvajal 1
  4. José Manuel Sánchez- Vizcaíno 1
  1. 1 Universidad Complutense de Madrid
    info

    Universidad Complutense de Madrid

    Madrid, España

    ROR 02p0gd045

Journal:
Revista complutense de ciencias veterinarias

ISSN: 1988-2688

Year of publication: 2009

Volume: 3

Issue: 2

Pages: 69-78

Type: Article

More publications in: Revista complutense de ciencias veterinarias

Abstract

Bluetongue Virus disease is an infectous disease submitted to a sanitary control composed by several measures of prevention, and one of these measures is the vaccination of the sensible species. In the development of vaccines opposite to this disease, a new trend is the production of polyvalent vaccines by VLP's technology (virus like particles). This work has had as aim to value by clinical survey, 2 VLP vaccines, for serotypes 1 and 1+4. The results confirm the lack of fever, clinical signs and pathologic injuries in vaccinated animals opposite to control animals, which indicates that these new vaccines protect for the appearance of clinical signs.