La locura mixedematosa. El delirio que cura con levotiroxina
- Germán Strada Herrera 1
- Marta Pérez Lombardo 1
- Eduardo Barbudo del Cura 1
- María Dolores Saiz González 1
- 1 Hospital Clínico San Carlos, Madrid
ISSN: 1134-5934
Year of publication: 2019
Volume: 26
Issue: 1
Type: Article
More publications in: Psiquiatría biológica: Publicación oficial de la Sociedad Española de Psiquiatría Biológica
Abstract
Objective The aim of this article is to analyse, using a clinical case, the psychotic disorders related to hypothyroidism. Case report The case is presented of a 51-year-old woman who was admitted to the hospital with an acute psychotic disorder, as well as paranoid delusions and hallucinatory behaviour. The evaluation revealed a severe hypothyroid state, for which the patient was treated with hormone therapy and antipsychotics, resulting in full clinical remission. Results The occurrence of mental disorders, especially mood disorders, during thyroid diseases have been known for a century, while psychotic disorders associated with thyroid diseases are rarely described. Conclusions This case highlights the role of thyroid hormone balance in the onset of psychotic manifestations, and emphasises the need to assess the functionality of this endocrine gland in the context of the aetiological diagnosis of psychosis.