Análisis retrospectivo en pacientes con cáncer de vesícula biliartratamiento quirúrgico y supervivencia en función del estadio tumoral
- Iago Justo Alonso 1
- Alberto A. Marcacuzco Quinto 1
- Oana Anisa Nutu 1
- Alejandro Manrique Municio 1
- Jorge Calvo Pulido 1
- Óscar Caso 1
- Félix Cambra Molero 1
- Álvaro García-Sesma Pérez-F 1
- Luis Carlos Jiménez Romero 1
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1
Hospital Universitario 12 de Octubre
info
ISSN: 2340-416, 1130-0108
Year of publication: 2018
Volume: 110
Issue: 8
Pages: 485-492
Type: Article
More publications in: Revista Española de Enfermedades Digestivas
Abstract
Introduction: gallbladder cancer is the most common biliary neoplasm and the sixth most common tumor of the digestive system. The disease has an ominous prognosis, with a 5-year survival rate of approximately 5%. It is usually diagnosed late and surgical resection is the only potential cure. Methods: a retrospective study was carried out in 92 patients with a pathological diagnosis of gallbladder cancer from January 2000 to January 2016. Results: the mean age of cases was 72 ± 11 years; 64 subjects were females and 28 were males. Symptoms at admission included abdominal pain (78%), anorexia (77%), nausea (76%) and jaundice (45%). Surgery was indicated in 92 (100%) patients and 59 (64%) underwent a curative/intent resection. The initial surgical procedures included simple cholecystectomy in 69 (75%) cases and extended cholecystectomy in eleven (11%) subjects. Rescue surgery was performed in 15 patients with tumor tissue in the cholecystectomy specimen; ten individuals underwent an R0 curative resection. Adjuvant therapy was administered in 30 (33%) patients. The median survival in our series was 12.5 months, with survival rates of 57%, 30% and 20% at one, three and five years, respectively. Conclusion: to conclude, surgical treatment with a complete tumor resection should be considered for all patients, provided that their clinical status allows it.