Rapamycin reverses age-related increases in mitochondrial ROS production at complex I, oxidative stress, accumulation of mtDNA fragments inside nuclear DNA, and lipofuscin level, and increases autophagy, in the liver of middle-aged mice

1. Martínez-Cisuelo, V.
2. Gómez, J.
3. García-Junceda, I.
4. Naudí, A.
5. Cabré, R.
6. Mota-Martorell, N.
7. López-Torres, M.
8. González-Sánchez, M.
9. Pamplona, R.
10. Barja, G.