Accidente isquémico transitorio tras espaciar la dosis de alirocumab¿es recomendable reducir las dosis de iPCSK9 ante c-LDL muy bajos?
- Piqueras Ruiz, Sandra 1
- Parra Virto, Alejandro
- Torres do Rego, Ana
- Demelo Rodríguez, Pablo
- Álvarez-Sala Walther, Luis 2
- 1 Departamento de Medicina Interna, Hospital General Universitario Gregorio Marañón, Madrid, España
- 2 Unidad de Riesgo Cardiovascular y Lípidos, Departamento de Medicina Interna, Hospital General Universitario Gregorio Marañón, Universidad Complutense, Madrid, España
ISSN: 0214-9168, 1578-1879
Argitalpen urtea: 2020
Alea: 32
Zenbakia: 1
Orrialdeak: 30-32
Mota: Artikulua
Beste argitalpen batzuk: Clínica e investigación en arteriosclerosis
Laburpena
Inhibitors of the protein PCSK9, available since 2015, are capable of reducing the concentration of low density lipoprotein cholesterol by 40 to 70%, thus reducing the cardiovascular risk. The present case reports an adverse cardiovascular event that appeared when spacing out the administration of lipid-lowering treatment. A discussion will be presented on the importance of maintaining low cholesterol levels in order to achieve a greater benefit, according to the latest published clinical studies.