Curación de la hepatitis autoinmune asociada a hepatitis C con antivirales de acción directa

  1. Laura López Couceiro 1
  2. Elena Gómez Domínguez 1
  3. Raquel Muñoz Gómez 1
  4. Gregorio Castellano Tortajada 1
  5. Carolina Ibarrola Andrés 1
  6. Inmaculada Fernández 1
  1. 1 Hospital Universitario 12 de Octubre. Madrid
Journal:
Revista Española de Enfermedades Digestivas

ISSN: 2340-416,  1130-0108

Year of publication: 2019

Volume: 111

Issue: 2

Pages: 159-161

Type: Article

DOI: 10.17235/REED.2018.5528/2018 DIALNET GOOGLE SCHOLAR

More publications in: Revista Española de Enfermedades Digestivas

Abstract

The use of direct-acting antivirals (DAA) for the hepatitis C virus (HCV) has yielded a significant improvement in the treatment of autoimmune hepatitis (AIH) associated with HCV infection. Interferon was the cornerstone of HCV therapy before the introduction of these agents into the clinical practice. Herein, we report the case of an HCV-infected patient who developed an interferon-induced AIH and since then, has received immunosuppressive therapy. Administration of DAA resulted in a sustained virologic response (SVR) and clinical AIH remission which allowed a discontinuation of immunosuppressive treatment.

Data source: Dialnet