La Actividad Física Protege de la Obesidad a los Escolares Genéticamente Predispuestos

  1. Noemí López Ejeda 1
  2. Jesús Román Martínez 1
  3. Antonio Villarino 1
  4. María Dolores Cabañas 1
  5. Marisa González Montero de Espinosa 1
  6. Luis Miguel López Mojares 2
  7. Juan Francisco Romero Collazos 1
  8. Consuelo Prado 1
  9. Ana Alaminos 1
  10. María Dolores Marrodán 1
  1. 1 Universidad Complutense de Madrid
    info

    Universidad Complutense de Madrid

    Madrid, España

    ROR 02p0gd045

  2. 2 Universidad Europea de Madrid
    info

    Universidad Europea de Madrid

    Madrid, España

    ROR https://ror.org/04dp46240

Revista:
Kronos: revista universitaria de la actividad física y el deporte

ISSN: 1579-5225

Año de publicación: 2020

Volumen: 19

Número: 1

Páginas: 2-2

Tipo: Artículo

Otras publicaciones en: Kronos: revista universitaria de la actividad física y el deporte

Resumen

Se analizó el perfil antropométrico y la composición corporal en 212 escolares españoles (10,81 ± 1,67 años de edad), junto a su nivel de actividad física y sedentarismo. Además se calculó su puntuación de riesgo genético para la obesidad a partir de 10 SNPs. Se constató que entre los escolares con perfil genético de mayor predisposición a la obesidad (RG >6), el IMC promedio de los considerados “activos” (más de 60 minutos diarios) fue de 18,44 ± 2,62 Kg/m2, frente al 21,46 ± 3,70 de los no activos. El %GC, también varió entre el 26,14 ± 7,19 de los primeros y el 28,25 ± 6,69 de los segundos. Los escolares menos sedentarios (≤ 2h/día) presentaron un IMC más bajo que los más sedentarios (>2 h/día): 18,73 ± 6,56 Kg/m2 frente a 20,79 ± 3,87 respectivamente. El %GC varió entre 26,41 ± 7,19 y el 27,72 ± 7,04 entre el primer y segundo grupo. Por tanto, puede afirmarse que el incremento de la actividad física y la reducción del sedentarismo, juegan un papel preponderante en la prevención del sobrepeso y el exceso de adiposidad, incluso cuando los sujetos manifiestan una condición genética adversa que les predispone a ser obesos.

Referencias bibliográficas

  • Aranceta-Bartrina, J., Gianzo-Citores, M., Pérez-Rodrigo, C. (2019). Prevalencia de sobrepeso, obesidad y obesidad abdominal en poblaciónespañola entre 3 y 24 años. Estudio ENPE. Rev Esp Cardiol, http://dx. doi.org/10.1016/j.recesp.2019.07.011.
  • Brook, C.G.D. (1971). Determination of body composition of children from skinfold measurements. Arch Dis Child, 46, 182-4.
  • Cole, T.J., Flegan, K.M., Nicholls, D., Jackson, A.A. (2007). Body mass index cut offs to define thinness in children and adolescents: international survey. BMJ, 335, 194.
  • Cole, T.J., Bellizzi, M.C., Flegal, K.M., Dietz, WH. (2000). Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ, 320, 1240.
  • Corella, D., Ortega-Azorín, C., Sorlí, J.V. et al. (2012). Statistical and Biological Gene-Life style Interactions of MC4R and FTO with Diet and Physical Activity on Obesity: New Effects on Alcohol Consumption. PLoS ONE, 7(12), e52344.
  • Durnin, J.V., Rahaman, M.M. (1967). The assessment of the amount of fat in the human body from measurements of skinfold thickness. Br J Nut, 21(3), 681-9.
  • Fernández, J.R., Redden, D.T., Pietrobelli, A., Allison, A.B. (2004). Waist circumference percentiles in nationally representative samples of african-american, european-american and mexican-american children and adolescents. J Pediatr, 145, 439-44.
  • Garrido-Miguel, M., Cavero-Redondo, I., Alvarez-Bueno, C. et al. (2019). Prevalence and Trends of Overweight and Obesity in European Children From 1999 to 2016. A Systematic Review and Meta-analysis. JAMA Pediatr. Doi: 10.1001/jamapediatrics.2019.2430
  • Guo, G., Liu, H., Wang, L., Shen, H., Hu, W. (2015). The genome-wide influence on human BMI depends on physical activity, life course, and historical period. Demography, 52, 1651-70
  • Carter, J.E.L., Heath, B.H. (1990). Somatotyping. Development and applications. En: Lasker, GW., Mascie-Taylor, CGN., Roberts, DF. eds. Cambridge studies in biological anthropology, 5. New York: Cambridge University Press.
  • Jääskeläinen, A., Schwab, U., Kolehmainen, M. et al. (2013). Meal frequencies modify the effect of common genetic variants on body mass index in adolescents of the Northern Finland Birth Cohort 1986. PlosOne, 8(9), e73802.
  • Johnson, W., Ong, K.K., Elks, C.E. et al. (2014). Modification of genetic influences on adiposity between 36 and 63 years of age by physical activity and smoking in the 1946 British Birth Cohort Study. Nutr Diab, 4, e136.
  • Kilpeläinen, T.O., Qi, L., Brage, S. et al. (2011). Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PlosMed 8(11), e1001116.
  • Li, L., Yin, J., Cheng, H. et al. (2016). Identification of genetic and environmental factors predicting metabolically healthy obesity in children: Data from the BCAMS study. J Clin Endocrinol Metab, 101(4), 1816-25.
  • Li, S., Zhao, J.H., Luan, J. et al. (2010). Physical Activity Attenuates the Genetic Predisposition to Obesity in 20,000 Men and Women from EPIC-Norfolk Prospective Population Study. PlosMed, 7(8), e1000332.
  • Liaw, Y.C., Liaw, Y.P., Lan, T.H. (2019). Physical Activity Might Reduce the Adverse Impactsof the FTO Gene Variant rs3751812 on the Body Mass Index of Adults in Taiwan. Genes, 10, 354; doi: 10.3390/genes10050354
  • Mielgo-Ayuso, J., Aparicio-Ugarriza, R., Castillo, A., et al. (2017). Sedentary behavior among Spanish children and adolescents: findings from the ANIBES Study. BMC Public Health, 17, 94; doi: 10.1186/s12889-017-4026-0.
  • NCBI - National Center for Biotechnology Information (2013). 1000 Genomes Browser. Alignment and genotype data from Hap Map Phase III, 3 may 2013 call set. Recuperado de: https://www.ncbi.nlm.nih.gov/variation/tools/1000genomes/
  • OMS (2017). World Health Organization. Comunicado de Prensa. La obesidad entre los niños y los adolescentes se ha multiplicado por 10 en los cuatro últimos decenios. Recuperado de: https://www.who.int/es/news-room/detail/11-10-2017-tenfold-increase-in-childhood-and-adolescent-obesity-in-four-decades-new-study-by-imperial-college-london-a
  • OMS (2016). WHO – World Health Organization. Report of the commission on ending childhood obesity. Recuperado de: http://apps.who.int/iris/bitstream/10665/204176/1/9789241510066_eng.pdf
  • OMS (2014). WHO – World Health Organization. Facts and figures on childhood obesity. Commision on Ending Childhood Obesity. Recuperado de: http://www.who.int/end-childhood-obesity/facts/en/
  • OMS (2011). WHO – World Health Organization. Global Strategy on Diet, Physical Activity and Health. Information sheet: global recommendations on physical activity for health 5 - 17 years old. Recuperado de: http://www.who.int/dietphysicalactivity/publications/recommendations5_17years/en
  • Parfenteva, O.I., Grot, D., Scheffler, C., Zaharova, M.F. (2019). Influence of the A/T polymorphism of the FTO gene and sport specializations on the body composition of young Russian athletes. Anthropol Anz. 76(5), 401-408.
  • Qi, Q., Li, Y., Chomistek, A.K. et al. (2012). Television watching, leisure-time physical activity and the genetic predisposition in relation to body mass index in women and men. Circulation, 126 (15), 1821-7.
  • Reddon, H., Gersten, H.C., Engert, J.C. (2016). Physical activity and genetic predisposition to obesity in a multiethnic longitudinal study. Sci Rep, 6, 18672.
  • Richardson, A.S., North, K.E., Graff, M. et al. (2014). Moderate to vigorous physical activity interactions with genetic variants and body mass index in a large US ethnically diverse cohort. Pediatr Obes, 9(2), e35-46.
  • Ruiz, J.R., Labayen, I., Ortega, F.B. et al. (2010). Attenuation of the effect of the FTO rs9939609 polymorphism on total and central body fat by physical activity in adolescents: the HELENA study. Arch Pediatr Adolesc Med, 164(4), 328-33.
  • Santos Beneit, G., Marrodán, M.D. (2019). ¿Estamos en el camino correcto para reducir la obesidad infantil? Rev. Esp. Cardiol. DOI: 10.1016/j.recesp.2019.10.004
  • SBRN- Sedentary Behaviour Research Network (2012). Letter to the editor: Standardized use of theterms “sedentary‟ and “sedentary behaviours‟. Appl Physiol Nutr Metab, 37, 540–2.
  • Song, J.Y., Song, Q.Y., Wang, S. et al. (2017). Physical activity and sedentary behaviors modify the association between melanocortin 4 receptor gene variant and obesity in Chinese children and adolescents. PlosOne, 12(1), e0170062.
  • Tremblay, M.S., Barne, J.D., Gonzalez, S.A. et al. (2016). Global Matrix 2. 0: reportcard gradesonthephysicalactivity of children and youth comparing 38 countries. J Phys Act Health, 13(11 Suppl 2), S343–S366.
  • Weiner, J.S., Lourie J.A. (1981). Practical human biology. Londres: AcademicPress.
  • World Medical Association (2013). Wordl Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA, 310 (20), 2191-4.
  • Xi, B., Cheng, H., Shen, Y. et al. (2012). Physical activity modifies the associations between genetic variants and hypertension in the Chinese children. Atherosclerosis, 225, 376-80.
  • Zhu, J., Loos, R.J.F., Zong, G. et al. (2014). Associations of genetic risk score with obesity and related traits and the modifying effect of physical activity in a Chinese Han Population. PlosOne, 9(3), e91442.