Mutational study of the "catalytic tetrad" of DNA topoisomerase IB from the hemoflagellate Leishmania donovani: Role of Asp-353 and Asn-221 in camptothecin resistance

  1. Diaz-González, R.
  2. Pérez-Pertejo, Y.
  3. Pommier, Y.
  4. Balaña-Fouce, R.
  5. Reguera, R.M.
Journal:
Biochemical Pharmacology

ISSN: 0006-2952

Year of publication: 2008

Volume: 76

Issue: 5

Pages: 608-619

Type: Article

DOI: 10.1016/J.BCP.2008.06.019 GOOGLE SCHOLAR