Metástasis coroideas de carcinoma de mamaDiagnóstico y seguimiento mediante tomografía de coherencia óptica y angiofluoresceingrafía y autofluorescencia con HRA-II (Heidelberg Retina Angiograph)

  1. M.J. Pérez-Álvarez
  2. P. Arriola-Villalobos
  3. J. Reche-Frutos
  4. J. García-Sánchez
Journal:
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Year of publication: 2009

Volume: 84

Issue: 5

Pages: 267-270

Type: Article

DOI: 10.4321/S0365-66912009000500009 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Archivos de la Sociedad Española de Oftalmologia

Abstract

Clinical case: A 69-year-old woman developed choroidal metastasis from a breast carcinoma 2 years after the initial diagnosis, surgery and chemotherapy. After treatment with palliative chemotherapy and external radiotherapy, we used fluorescein angiography (FA) and optical coherence tomography (OCT) to evaluate the resolution of the serous retinal detachment, as well as a later relapse in the optic nerve. Discussion: OCT is useful in the follow-up of choroidal metastasis after treatment. However, OCT imaging is limited by the initial choroidal location of metastasis. The autofluorescence can detect exudative tumoral activity even without obvious changes in OCT or FA.

Bibliographic References

  • Barak, A, Neudorfer, M, Heilweil, G, Merimsky, O, Lowenstein, A, Inbar, M. (2007). Decreased prevalence of asymptomatic choroidal metastasis in disseminated breast and lung cancer: argument against screening. Br J Ophthalmol. 91. 74-75
  • Bottke, D, Wiegel, T, Kreusel, KM, Bornfeld, N, Schaller, G, Hinkelbein, W. (2000). Radiotherapy of choroidal metastases in patients with disseminated cancer. Onkologie. 23. 572-575
  • Arevalo, JF, Fernandez, CF, Garcia, RA. (2005). Optical coherence tomography characteristics of choroidal metastasis. Ophthalmology. 112. 1612-1619
  • Shields, JA, Shields, CL, Singh, AD. (2000). Metastatic neoplasms in the optic disc: the 1999 Bjerrum Lecture: part 2. Arch Ophthalmol. 118. 217-224
  • Jork, J, Bindewald, A, Dithmar, S, Holz, F. (2005). Digital simultaneous fluorescein and indocyanine green angiography, autofluorescence, and red-free imaging with a solid-state laser-based confocal scanning laser ophthalmoscope. Retina. 25. 405-416