Niveles óptimos de colesterol en los pacientes con dislipemia. Revisión sistemática de la evidencia

  1. C. Escobar 1
  2. V. Barrios 2
  3. L. Pérez de la Isla 3
  1. 1 Hospital Universitario La Paz, Madrid, España
  2. 2 Hospital Universitario Ramón y Cajal, Madrid, España
  3. 3 Hospital Clínico San Carlos de Madrid
    info

    Hospital Clínico San Carlos de Madrid

    Madrid, España

    ROR https://ror.org/04d0ybj29

Revista:
Semergen: revista española de medicina de familia

ISSN: 1138-3593

Año de publicación: 2018

Número: 1

Páginas: 42-49

Tipo: Artículo

DOI: 10.1016/J.SEMERG.2017.08.006 DIALNET GOOGLE SCHOLAR

Otras publicaciones en: Semergen: revista española de medicina de familia

Resumen

La dislipidemia constituye uno de los principales factores de riesgo para el desarrollo de la aterosclerosis. Diversos estudios han demostrado que el colesterol LDL, cuanto más bajo, mejor. Las evidencias actuales muestran que los objetivos de colesterol LDL recomendados por las guías de práctica clínica son beneficiosos y seguros, si bien existen datos consistentes que muestran que reducciones mayores podrían aportar beneficios cardiovasculares adicionales, sin un aumento en el riesgo de los efectos adversos. Desafortunadamente, el control de la dislipidemia es muy pobre en la actualidad. Si bien las estatinas son el tratamiento de elección en la mayoría de los pacientes con dislipidemia, el arsenal terapéutico hipolipidemiante actual dispone de diferentes alternativas que reducen eficazmente el colesterol LDL y que, solas o en combinación, permitirían lograr los objetivos de control de colesterol LDL en la gran mayoría de los pacientes.

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