Predictores de respuesta al tratamiento con naltrexona en dependientes de alcohol

  1. F. Arias Horcajadas 1
  2. E. Ochoa Mangado 2
  3. M. A. Torres Hernández 3
  1. 1 Psiquiatra. Fundación Hospital de Alcorcón. Madrid.
  2. 2 Servicio de Psiquiatría. Hospital Ramón y Cajal. Madrid.
  3. 3 Unidad de Alcoholismo y Toxicomanías. Salud Mental Área 8. Valencia.
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Revista:
Trastornos adictivos: Organo Oficial de la Sociedad española de Toxicomanías

ISSN: 1575-0973

Any de publicació: 2000

Volum: 2

Número: 3

Pàgines: 194-200

Tipus: Article

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Altres publicacions en: Trastornos adictivos: Organo Oficial de la Sociedad española de Toxicomanías

Resum

Objective: evaluate predictors of response to naltrexone in alcoholism. Material and methods: a national, multicentric, observational, prospective, and naturalistic study was developed. We evaluated sociodemographical and toxicological characteristics and we applied next scales and interviews: EuropASI, EIDA, Ciwa-Ar and Hamilton Depression Rating Scale. We evaluated 173 outpatients in treatment with 50 mg by day of naltrexone and different psychotherapeutic modalities. Follow-up of six months was carried out. A logistic regression model with predictive objective of relapse was developed. Results: alcohol dependence severity from EuropASI, use of psychotherapy and daily use of alcohol were predictors of response. Conclusions: it's neccesary more studies that delimited alcoholics subgroups with favourable response to naltrexone and predictors of response to different therapeutic alternatives to alcoholism.

Fuente de los datos: Dialnet