Utilidad de antibioticoterapia asociada a cirugía en el tratamiento de adenopatías por micobacterias no tuberculosas

  1. F.J. Sanz Santaeufemia
  2. J. T. Ramos Amador
  3. E. Giangaspro
  4. J.M. Sánchez Granados
  5. E. Palenque
  6. María Isabel González Tomé
Journal:
Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría ( AEP )

ISSN: 1695-4033 1696-4608

Year of publication: 2005

Volume: 62

Issue: 3

Pages: 282-285

Type: Article

More publications in: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría ( AEP )

Abstract

Background In recent years, lymphadenitis caused by atypical mycobacteria (also called nontuberculous mycobacteria [NTMB] or, more recently, environmental) have played a significant role in the differential diagnosis of adenitis in non-immunocompromised children. Objectives To describe the clinical and pathological findings in childhood NTMB adenitis and study the possible usefulness of antimicrobial therapy in addition to surgery. Methods We present eight cases of neck lymphadenitis occurring over a 5-year period. All of the children received combined chemotherapy, and six also underwent surgery. Of the two remaining patients, the parents of one child refused surgery and a watchful approach was adopted in the other. Results Complete clinical recovery was achieved in all patients except one who did not undergo surgery. Conclusions Prolonged administration of two antibiotics (of which one must be clarithromycin) in addition to surgery was well-tolerated and could be useful in patients with NTMB neck lymphadenitis.