Risk Factors Associated with Relapse in Major Depressive Disorder in Primary Care PatientsA Systematic Review

  1. Maider Prieto-Vila 1
  2. Francisco José Estupiñá 1
  3. Antonio Cano-Vindel 1
  1. 1 Universidad Complutense de Madrid
    info

    Universidad Complutense de Madrid

    Madrid, España

    ROR 02p0gd045

Revue:
Psicothema

ISSN: 0214-9915,  1886-144X

Année de publication: 2021

Volumen: 33

Número: 1

Pages: 44-52

Type: Article

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D'autres publications dans: Psicothema

Résumé

Background: Major Depressive Disorder (MDD) is highly recurrent. Most patients with MDD are treated in the Primary Care (PC) setting. The purpose of this systematic review was to identify risk factors associated with relapse of MDD in PC. Method: A systematic review of PsycINFO, PubMed, Web of Science and ScienceDirect, from 1978 to 2019, following PRISMA guidelines was conducted. Results: Eight studies fulfilling the eligibility criteria and 12 risk factors associated with relapse of MDD were found. Patients who showed a higher frequency of relapse were: 1) those with higher scores in neuroticism, disability, current MDD episode severity, and childhood abuse; 2) lower scores on extraversion, self-esteem, emotional role, physical functioning; 3) history of MDD relapse; 4) comorbidity; and 5) poorer adherence to antidepressant medication (ADM). In terms of treatment, ADM combined with cognitive behavioural therapy and psychoeducation was reported to produce fewer relapses, as was mindfulness-based cognitive therapy for patients with a higher score in childhood abuse. Conclusions: Despite the very varied nature of the studies, different risk factors associated with relapse were identified. However, more research is needed on this important problem, with randomized controlled trials.

Références bibliographiques

  • American Psychiatric Association (1994). Diagnostic and statistical manual of mental disorders (4th ed.). https://bit.ly/2XpiBsY
  • American Psychiatric Association (2000). Diagnostic and statistical manual of mental disorders (4th ed., text rev.). https://bit.ly/3bT8NN9
  • Andrews, G., & Peters, L. (1998). The psychometric properties of the composite international diagnostic interview. Social Psychiatry and Psychiatric Epidemiology, 33(2), 80-88. https://doi.org/10.1007/s001270050026
  • Beck, A.T., Ward, C.H., Mendelson, M., Mock, J., & Erbaugh, J. (1961). An inventory for measuring depression. Archives of General Psychiatry, 4(6), 561-571. https://doi.org/10.1001/archpsyc.1961.01710120031004
  • Beck, A. T., Steer, R. A., & Brown, G. K. (1996). Manual for the Beck depression inventory-II. Psychological Corporation. https://bit.ly/2Tub62S
  • Bernstein, D. P., Fink, L., Handelsman, L., Foote, J., Lovejoy, M., Wenzel, K., Sapatero, J., & Ruggiero, J. (1994). Initial reliability and validity of a new retrospective measure of child abuse and neglect. The American Journal of Psychiatry, 151(8), 1132-1136. https://doi.org/10.1176/ajp.151.8.1132
  • Bockting, C. L., Hollon, S. D., Jarrett, R. B., Kuyken, W., & Dobson, K. (2015). A lifetime approach to major depressive disorder: The contributions of psychological interventions in preventing relapse and recurrence. Clinical Psychology Review, 41, 16-26. https://doi.org/10.1016/j.cpr.2015.02.003
  • Bouman, T. K., Luteijn, F., Albersnagel, F. A., & Van der Ploeg, F. A. (1985). Enige ervaringen met de Beck depression inventory (BDI). [some experiences with Beck’s depression inventory (BDI)]. Gedrag: Tijdschrift Voor Psychologie, 13(2), 13-24. https://bit.ly/36yj3JT
  • Brooks, R. (1996). EuroQol: The current state of play. Health Policy, 37(1), 53-72. https://doi.org/10.1016/0168-8510(96)00822-6
  • Buckman, J. E. J., Underwood, A., Clarke, K., Saunders, R., Hollon, S. D., Fearon, P., & Pilling, S. (2018). Risk factors for relapse and recurrence of depression in adults and how they operate: A four-phase systematic review and meta-synthesis. Clinical Psychology Review, 64, 13-38. https://doi.org/10.1016/j.cpr.2018.07.005
  • Burcusa, S. L., & Iacono, W. G. (2007). Risk for recurrence in depression. Clinical Psychology Review, 27(8), 959-985. https://doi.org/10.1016/j.cpr.2007.02.005
  • Cajal, B., Jiménez, R., Gervilla, E., & Montaño, J. J. (2020). Doing a systematic review in health sciences. Clínica y Salud, 31(2), 77-83. https://doi.org/10.5093/clysa2020a15
  • Cano-Vindel, A. (2011). Emotional disorders in primary care. Ansiedad y Estrés, 17(1), 75-97. https://bit.ly/33oKhD0
  • Clark, D. O., Von Korff, M., Saunders, K., Baluch, W. M., & Simon, G. E. (1995). A chronic disease score with empirically derived weights. Medical Care, 33(8), 783-795. https://doi.org/10.1097/00005650-199508000-00004
  • Clarke, K., Mayo-Wilson, E., Kenny, J., & Pilling, S. (2015). Can nonpharmacological interventions prevent relapse in adults who have recovered from depression? A systematic review and meta-analysis of randomised controlled trials. Clinical Psychology Review, 39, 58-70. https://doi.org/10.1016/j.cpr.2015.04.002
  • Conradi, H. J., Jonge, P. d., Kluiter, H., Smit, A., Meer, K. v. d., Jenner, J. A., van Os, T.W. D. P.; Emmelkamp, P. M. G., & Ormel, J. (2007). Enhanced treatment for depression in primary care: Long-term outcomes of a psycho-educational prevention program alone and enriched with psychiatric consultation or cognitive behavioral therapy. Psychological Medicine, 37(6), 849-862. https://doi.org/10.1017/S0033291706009809
  • Conradi, H. J., de Jonge, P., & Ormel, J. (2008). Prediction of the three-year course of recurrent depression in primary care patients: Different risk factors for different outcomes. Journal of Affective Disorders, 105(1), 267-271. https://doi.org/10.1016/j.jad.2007.04.017
  • Costa, P. T., & McCrae, R. R. (1985). The NEO personality inventory. Psychological Assessment Resources. https://bit.ly/36lOBlW
  • Costa, P. T., & McCrae, R. R. (1992). Revised NEO personality inventory (NEO-PI-R) and NEO fi ve-factor (NEO-FFI) inventory professional manual. Psychological Assessment Resources. https://bit.ly/3ggvuhw
  • Centre for Reviews and Dissemination (2009). CRD’s guidance for undertaking reviews in health care. York Publishing Services. https://bit.ly/3gnKwT0
  • Cuijpers, P., van Straten, A., van Schaik, A., & Andersson, G. (2009). Psychological treatment of depression in primary care: A metaanalysis. The British Journal of General Practice: The Journal of the Royal College of General Practitioners, 59(559), 51-60. https://doi.org/10.3399/bjgp09X395139
  • Cuijpers, P., Berking, M., Andersson, G., Quigley, L., Kleiboer, A., & Dobson, K. S. (2013). A meta-analysis of cognitive-behavioural therapy for adult depression, alone and in comparison, with other treatments. The Canadian Journal of Psychiatry / La Revue Canadienne De Psychiatrie, 58(7), 376-385. https://doi.org/10.1177/070674371305800702
  • Cuijpers, P., Noma, H., Karyotaki, E., Vinkers, C. H., Cipriani, A., & Furukawa, T. A. (2020). A network meta‐analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression. World Psychiatry, 19(1), 92-107. https://doi.org/10.1002/wps.20701
  • De Graaf, L. E., Gerhards, S. A. H., Arntz, A., Riper, H., Metsemakers, J. F. M., Evers, S. M. A. A., Severens, J., L., Widdershoven, G., & Huibers, M. J. H. (2011). One-year follow-up results of unsupported online computerized cognitive behavioural therapy for depression in primary care: A randomized trial. Journal of Behavior Therapy and Experimental Psychiatry, 42(1), 89-95. https://doi.org/10.1016/j.jbtep.2010.07.003
  • De Jong, G. J., & Kamphuis, F. (1985). The development of a Rasch-type loneliness scale. Applied Psychological Measurement, 9(3), 289-299. https://doi.org/10.1177/014662168500900307
  • Derogatis, L. R., Lipman, R. S., Rickels, K., Uhlenhuth, E. H., & Covi, L. (1974). The Hopkins symptom checklist (HSCL): A self-report symptom inventory. Behavioral Science, 19(1), 1-15. https://doi.org/10.1002/bs.3830190102
  • Eaton, W. W., Shao, H., Nestadt, G., Lee, B. H., Bienvenu, O. J., & Zandi, P. (2008). Population-based study of fi rst onset and chronicity in major depressive disorder. Archives of General Psychiatry, 65(5), 513-520. https://doi.org/10.1001/archpsyc.65.5.513
  • Fernández, A., Haro, J. M., Codony, M., Vilagut, G., Martínez-Alonso, M., Autonell, J., Salvador-Carulla, L., Ayuso-Mateos, L., Fullana, M. A., & Alonso, J. (2006). Treatment adequacy of anxiety and depressive disorders: Primary versus specialised care in Spain. Journal of Affective Disorders, 96(1-2), 9-20. https://doi.org/10.1016/j.jad.2006.05.005
  • Frank, E., Prien, R. F., Jarrett, R. B., Keller, M. B., Kupfer, D. J., Lavori, P. W., Rush, J. A., & Weissman, M. M. (1991). Conceptualization and rationale for consensus defi nitions of terms in major depressive disorder: Remission, recovery, relapse, and recurrence. Archives of General Psychiatry, 48(9), 851-855. https://doi.org/10.1001/archpsyc.1991.01810330075011
  • Gopinath, S., Katon, W. J., Russo, J. E., & Ludman, E. J. (2007). Clinical factors associated with relapse in primary care patients with chronic or recurrent depression. Journal of Affective Disorders, 101(1-3), 57-63. https://doi.org/10.1016/j.jad.2006.10.023
  • Hardeveld, F., Spijker, J., De Graaf, R., Nolen, W. A., & Beekman, A. T. F. (2010). Prevalence and predictors of recurrence of major depressive disorder in the adult population. Acta Psychiatrica Scandinavica, 122(3), 184-191. https://doi.org/10.1111/j.1600-0447.2009.01519.x
  • The WHOQOL group (1998). Development of the World Health Organization WHOQOL-BREF Quality of Life Assessment. Psychological Medicine, 28(3), 551-558. https://doi.org/10.1017/S0033291798006667
  • Katon, W., Rutter, C., Ludman, E. J., Von Korff, M., Lin, E., Simon, G., Bush, T., Walker, M., & Unützer, J. (2001). A randomized trial of relapse prevention of depression in primary care. Archives of General Psychiatry, 58(3), 241-247. https://doi.org/10.1001/archpsyc.58.3.241
  • Kuyken, W., Hayes, R., Barrett, B., Byng, R., Dalgleish, T., Kessler, D., Lewis, G., Watkins, E., Brejcha, C., Cardy, J., Causley, A., Cowderoy, S., Evans, A., Gradinger, F., Kaur, S., Lanhamh, P., Morant, N., Richards, J., Shahb, P., . . . Byford, S. (2015). Effectiveness and costeffectiveness of mindfulness-based cognitive therapy compared with maintenance antidepressant treatment in the prevention of depressive relapse or recurrence (PREVENT): A randomised controlled trial. The Lancet, 386(9988), 63-73. https://doi.org/10.1016/s0140-6736(14)62222-4
  • Kuyken, W., Warren, F. C., Taylor, R. S., Whalley, B., Crane, C., Bondolfi , G., Hayes, R., Huijbers, M., Ma, H., Schweizer, S., Segal, Z., Speckens, A., Teasdale, J. D., Van Heeringen, K., Williams, M., Byford, S., Byng, R., & Dalgleish, T. (2016). Efficacy of mindfulness-based cognitive therapy in prevention of depressive relapse: An individual patient data meta-analysis from randomized trials. JAMA Psychiatry, 73(6), 565- 574. https://doi.org/10.1001/jamapsychiatry.2016.0076
  • Law, M., Sterwart, D., Pollock, N., Letts, L., Bosch, J., & Westmorland, M. (1998). Critical Review Form, Quantitative Studies. McMaster University. https://srs-mcmaster.ca/wp-content/uploads/2015/04/Critical-ReviewForm-Quantitative-Studies-English.pdf
  • Linde, K., Sigterman, K., Kriston, L., Rücker, G., Jamil, S., Meissner, K., & Schneider, A. (2015). Effectiveness of psychological treatments for depressive disorders in primary care: systematic review and metaanalysis. The Annals of Family Medicine, 13(1), 56-68. https://doi.org/10.1370/afm.1719
  • Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & Group, T. P. (2009). Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. PLoS Medicine, 6(7), e1000097. https://doi.org/10.1371/journal.pmed.1000097
  • Morisky, D. E., Green, L. W., & Levine, D. M. (1986). Concurrent and predictive validity of a self-reported measure of medication adherence. Medical Care, 24(1), 67-74. https://doi.org/10.1097/00005650-198601000-00007
  • Piet, J., & Hougaard, E. (2011). The effect of mindfulness-based cognitive therapy for prevention of relapse in recurrent major depressive disorder: A systematic review and meta-analysis. Clinical Psychology Review, 31(6), 1032-1040. https://doi.org/10.1016/j.cpr.2011.05.002
  • Reimherr, F. W., Amsterdam, J. D., Quitkin, F. M., Rosenbaum, J. F., Fava, M., Zajecka, J., Beasley, C., Michelson, D., Roback, P., & Sundell, K. (1998). Optimal length of continuation therapy in depression: A prospective assessment during long-term fl uoxetine treatment. The American Journal of Psychiatry, 155(9), 1247-1253. https://doi.org/10.1176/ajp.155.9.1247
  • Rosenberg, M. (1965). Rosenberg self-esteem scale (RSE). Acceptance and commitment therapy. Measures package, 61(52), 18. https://bit.ly/30sbMcU
  • Ruiz-Rodríguez, P., Cano-Vindel, A., Muñoz Navarro, R., Medrano, L., Moriana, J. A., Buiza Aguado, C., Jiménez Cabré, G., & GonzálezBlanch, C. (2017). Impacto económico y carga de los trastornos mentales comunes en España: una revisión sistemática y crítica. Ansiedad y Estrés, 23(2-3), 118-123. https://doi.org/10.1016/j.anyes.2017.10.003
  • Rush, A. J., Kraemer, H. C., Sackeim, H. A., Fava, M., Trivedi, M. H., Frank, E., Ninan, P. T., Thase, M. E., Gelenberg, A. J., Kupfer, D. J., Regier, D. A., Rosenbaum, J. F., Ray, O., & Schatzberg, A. F. (2006). Report by the ACNP task force on response and remission in major depressive disorder. Neuropsychopharmacology, 31(9), 1841-1853. https://doi.org/10.1038/sj.npp.1301131
  • Santoft, F., Axelsson, E., Öst, L., Hedman-Lagerlöf, M., Fust, J., & HedmanLagerlöf, E. (2019). Cognitive behaviour therapy for depression in primary care: Systematic review and meta-analysis. Psychological Medicine, 49(8), 1266-1274. https://doi.org/10.1017/S0033291718004208
  • Sheehan, D. V. (1983). Sheehan disability scale. Handbook of psychiatric measures, 2, 100-102. https://bit.ly/3e7uXwE
  • Solomon, D. A., Keller, M. B., Leon, A. C., Mueller, T. I., Lavori, P. W., Shea, M. T., Corvell, W., Warshaw, M., Turvey, C., Maser, J. D., & Endicott, J. (2000). Multiple recurrences of major depressive disorder. The American Journal of Psychiatry, 157(2), 229-233. https://doi.org/10.1176/appi.ajp.157.2.229
  • Twomey, C., O’Reilly, G., & Byrne, M. (2015). Effectiveness of cognitive behavioural therapy for anxiety and depression in primary care: A metaanalysis. Family Practice, 32(1), 3-15. https://doi.org/10.1093/fampra/cmu060
  • Verhoeven, F. E. A., Wardenaar, K. J., Ruhé, H. G. E., Conradi, H. J., & de Jonge, P. (2018). Seeing the signs: Using the course of residual depressive symptomatology to predict patterns of relapse and recurrence of major depressive disorder. Depression and Anxiety, 35(2), 148-159. https://doi.org/10.1002/da.22695
  • Wardenaar, K. J., Conradi, H., & de Jonge, P. (2014). Data-driven course trajectories in primary care patients with major depressive disorder. Depression and Anxiety, 31(9), 778-786. https://doi.org/10.1002/da.22228
  • Ware Jr., J. E. (2000). SF-36 health survey update. Spine, 25(24), 3130- 3139. https://doi.org/10.1097/00007632-200012150-00008
  • Williams, J. B., Gibbon, M., First, M. B., Spitzer, R. L., Davies, M., Borus, J., Howes, M. J., Kane, J., Pope, H. G., Rounsaville, B., & Wittchen, H. (1992). The structured clinical interview for DSM-III-R (SCID): II. multisite test-retest reliability. Archives of General Psychiatry, 49(8), 630-636. https://doi.org/10.1001/archpsyc.1992.01820080038006
  • Williams, J. B. W., Kobak, K. A., Bech, P., Engelhardt, N., Evans, K., Lipsitz, J., Jason, O., Jay, P., & Kalali, A. (2008). The GRID-HAMD: Standardization of the Hamilton depression rating scale. International Clinical Psychopharmacology, 23(3), 120-129. https://doi.org/10.1097/YIC.0b013e3282f948f5
  • Wittchen, H. (1994). Reliability and validity studies of the WHO-composite international diagnostic interview (CIDI): A critical review. Journal of Psychiatric Research, 28(1), 57-84. https://doi.org/10.1016/0022-3956(94)90036-1
  • World Health Organization (2017). Depression and Other Common Mental Disorders: Global Health Estimates. http://apps.who.int/iris/bitstream/handle/10665/254610/WHO-MSDMER-2017.2-eng.pdf
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