Utilidad de los valores de función ventricular obtenidos mediante gated-SPECT post-estrés en población diabética con sospecha clínica de cardiopatía isquémica
- Sebastián Ruiz Solís
- Mónica Maure Rico
- Montserrat Cortés Romera
- Víctor Manuel Poblete García
- Begoña Rodríguez Alfonso
- Mª del Prado Talavera Rubio
- Azahara Palomar Muñoz
- Ana María García Vicente
- Cristobal Martínez Delgado
- Angel Soriano Castrejón
ISSN: 0212-6982
Year of publication: 2008
Volume: 27
Issue: 5
Pages: 340-349
Type: Article
More publications in: Revista española de medicina nuclear
Abstract
Objective. To assess the clinical usefulness of left ventricular function values obtained using post-stress myocardial perfusion gated-SPECT in diabetic patients with suspected ischaemic heart disease (IHD). Materials and methods. Sixty-one patients with diabetes mellitus (DM), with clinical suspicion of IHD and no previous history of heart disease were studied. Ergometric or pharmacological post-stress myocardial perfusion gated-SPECT was performed on all patients. The relationship between the ejection fraction values and ventricular volumes, and the perfusion study results, final diagnosis, severity of the perfusion defects and the clinical evolution was studied. The mean follow-up time was 14 months. Results. All the ventricular function values independently showed significant differences between the groups with a normal and pathological perfusion study, and between groups with a final diagnosis of IHD and non-IHD. After multivariate logistic regression, the end-diastolic volume (EDV) was the only value which showed a statistical association with the pathological perfusion study, its severity and the final diagnosis of IHD. No statistical association was observed between the ventricular function values and the occurrence of cardiac events. Conclusions. All the ventricular function values obtained by gated-SPECT added diagnostic information to the post-stress myocardial perfusion study in the diabetic population with suspected IHD; however, only EDV showed a statistical association with the pathological perfusion study, severity of defects and the final diagnosis of IHD.