Membrana amniótica, revisión de su uso oftalmológico y resultados en los últimos cinco años (2013-2017) en Granada. Estudio preliminar

  1. Lacorzana-Rodríguez, J.
  2. García-Serrano, J.L.
  3. Gálvez Prieto-Moreno C.
  4. Castillo-Rodríguez, S.
  5. Lucena-Martín, J.A.
  6. Pozo-Jiménez, I.
Journal:
Actualidad médica

ISSN: 0365-7965

Year of publication: 2018

Tome: 103

Issue: 804

Pages: 82-86

Type: Article

DOI: 10.15568/AM.2018.804.OR05 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Actualidad médica

Abstract

Purpose: To analyze the results obtained from the amniotic membrane transplant for ophthalmological purposes in the province of Granada between the years 2013-2017 to identify possible variables that influence, to a greater or lesser extent, a good postoperative prognosis. Materials and methods: Retrospective study of case series. Forty-four patients with lesions on the ocular surface were studied, who received an amniotic membrane transplant between 2013-2017 in the province of Granada (Spain) with a minimum follow-up of 8 months. The patients presented: corneal abrasions, descemetoceles, perforations, recurrent pterygium, band keratopathies, nummular keratitis, symblepharon and recurrent ulcers. The variables collected in each case were: sex, age, date of transplant, technique used, number of amniotic membrane implanted in each patient, number of implanted amniotic membrane layers, type of amniotic membrane, reason for the transplant, were there complications?, when?, did you put a second amniotic membrane?, did you perform another intervention?, were there postoperative infections?, improvement in acuity visual, corneal transparency? and global success or failure of the intervention ?. For the statistical analysis, the results of the success group were compared with those of the failure group using the Mann-Whitney test, applying the Kendall test to identify correlation between groups. Results: Regarding the success or failure of the treatment, statistically significant differences were found between the success group and the failure group for the following variables: implant motive due to corneal perforation (most failed), existence of complications and corneal transparency, which correlated positively or negatively with the success of the transplant. With regard to these last two parameters (the absence of complications and a good corneal transparency) were related to postoperative success. Conclusion: This preliminary study suggests that amniotic membrane transplantation could be useful in ophthalmology, there being a clear association between the success of this technique and certain factors related to the evolution of the patient. Likewise, the amniotic membrane should not be used in isolation in patients with ocular perforation, due to the high risk of failure of the technique, being necessary to perform along with adjuvant treatments and recommended the study of more definitive treatments

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