Perfiles hormonales esteroideos durante el embarazo y la utilización de modelos matemáticos para la predicción del inicio del parto

Abstract

One of the main goals in obstetrics is the deeper knowledge of the events that occurs during pregnancy, in order to ensure a good fetal development that culminates with a transition to extrauterine life and adaptation to childhood and satisfactory maturity. The hormonal interaction is crucial for an adequate fetal evolution, being the second trimester an essential stage for the maturation of the organs and systems; and the third trimester necessary for childbirth preparation and extrauterine life. The physiological processes of pregnancy mainly depend on the interaction of different factors where the maternal-fetal endocrine systems havean essential role for the good fetal development. The placenta and the adrenal glands (fetal and maternal) are the organs responsible for the synthesis of large amounts of steroid hormones during the second and third trimesters of pregnancy. Exposure of the fetus to high amounts of steroid hormones canhave a negative impact on fetal development...