Enfermedades neurológicas y psiquiátricas en el anciano

  1. Viloria Jiménez, M. A.
Revue:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Année de publication: 2014

Titre de la publication: Enfermedades geriátricas

Serie: 11

Número: 62

Pages: 3659-3676

Type: Article

DOI: 10.1016/S0304-5412(14)70828-5 DIALNET GOOGLE SCHOLAR

D'autres publications dans: Medicine: Programa de Formación Médica Continuada Acreditado

Résumé

Neurological and psychiatric diseases have a high prevalence in the elderly with an estimate of about 12 % globally. These figures rise considerably in hospitalized population (40-50 %) and more in institutionalized elderly (70-94 %). In psychiatric hospitals, 27 % of patients are older than 65. Notably dementia, Parkinson's disease, cerebrovascular disease, depression, anxiety, delirium and sleep disorders, because of their frequency in this age group and their impact on quality of life of the patient and caregiver and socioeconomic.

Références bibliographiques

  • Aarsland D, Larsen JP, Lim NG, Janvin C, Karlsen K, Tandberg E. Range of neuropsychiatric disturbances in patients with Parkinson Disease. J Neurol Neurosurg Psychiatry. 1999;67:492-6.
  • Banerjee S, Smith SC, Lamping DL, Harwood RH, Foley B, Smith P. Quality of life in dementia: more than just cognition. An analisys of associations with quality of life in dementia. J Neurol Neurosurg Psychiatry. 2006;77:146-8.
  • Braak H, del Tredici K, Rub U, de Vos RA, Jansen Steur EN, Braak E. Staging of brain pathology related to sporadic Parkinson’s disease. Neurobiol Aging. 2003;24:197-211.
  • Buter TC, Van Den Hout A, Matthews FE, Larsen JP, Brayne C, Aarsland D. Dementia and survival on Parkinson disease: a 12 year population study. Neurology. 2008;70(13):1017-22.
  • Canovas P, García-Arilla Calvo E, Sanjoaquín Romero AC, Alarcón Co-rominas J. Delirium en ancianos hospitalizados. Med Clin. 2008;130(17): 679.
  • Casado I, Calatayud T. Epidemiología y factores de riesgo. Guía oficial para la práctica clínica en demencias: conceptos, criterios y recomendaciones. Barcelona: Prous Science; 2009. p. 23-50.
  • Cerejeira J, Firmino H, Vaz-Serra A, Mukaetova-Ladinska EB. The neuroinflammatory hypothesis of delirium. Acta Neuropathol. 2010;119(6): 737-54.
  • Clegg A, Young JB. Which medications to avoid in people at risk of delirium: a systematic review. Age Ageing. 2011;40:23-9.
  • Constantinescu R, Mondello S. Cerebrospinal fluid biomarker candidates for Parkinsonian disorders. Front Neurol. 2013;3:187.
  • Cummings JL, Mega M, Gray K, Rosenberg-Thompson S, Carusi DA, Gornbein J. The neuropsychiatric inventory. Comprehensive assessment of psychopatology in dementia. Neurology. 1994;44:2308-14.
  • Dewing P, Chiang CW, Sinchak K, Sim H, Fernagut PO, Kelly S. Direct regulation of adult brain function by the male specific factor SRY. Curr Biol. 2006;16:415-22.
  • Dubois B, Burn D, Goetz C. Diagnostic procedures for Parkinson disease dementia: recommendations from the Movement Disorder Society Task Force. Mov Disord. 2007;15:22
  • Eeles EM, Hubbard RE, White SV, O'Mahony MS, Savva GM, Bayer AJ Hospital use, institutionalisation and mortality associated with delirium. Age and Ageing. 2010;39(4):470-5.
  • Elie D. Using psychostimulants in end of life patients with hypoactive delirium and cognitive disorders: A literature review. Can J Psychiatry. 2010;55(6):386-93.
  • Forlenza OV, Diniz BS, Gattaz WF. Diagnosis and biomarkers of predementia in Alzheimer’s disease. BMC Medicine. 2010;8:89-102.
  • Formiga F, Riera-Mestre A, Chivite D, Pujol R. Delirium en pacientes mayores de 94 años con fractura de fémur. Rev Esp Geriatr Gerontol. 2008;43:154-6.
  • García Alberca JM, Lara JP, González Barón S, Barbancho MA, Porta D, Berthier M. Prevalencia y comorbilidad de síntomas neuropsiquiátricos en la enfermedad de Alzheimer. Actas Esp Psiquiatría. 2008;36:265-70.
  • Garnica Fernández A. Tratamiento no farmacológico de la Enfermedad de Parkinson en el anciano. Guía de buena práctica clínica en Geriatría. Enfermedad de Parkinson. Barcelona: SEGG, Elsevier Doyma; 2009. p. 73-85.
  • Gazewood JD, Richards DR, Clebak K. Parkinson disease: an updated. Am Fam Physician. 2013;87(4):267-73.
  • Gilman S. Parkinsonian syndromes. Clin Geriatr Med. 2006;22:827-42.
  • Goldman JS, MPhil MS, Hahn SE, LaRusse-Eckert S, Butson MB, Rumbaugh M. Genetic counseling and testing for Alzheimer disease: Joint practice guidelines of the American College of Medical Genetics and the National Society of Genetic Counselors. Genet Med. 2011;13(6): 597-605.
  • González M, de Pablo J, Fuente E, Valdés M, Peri JM, Nomdedeu M. Instrument for detection of delirium in general hospitals: adaptation of the confusion assessment method. Psychosomatics. 2004;45(5):426-31.
  • González Glaría B. Enfermedad de Parkinson y otros parkinsonismos. Tratado de Neuropsicogeriatría. Madrid: SEGG; 2010. p. 214-38.
  • Gorno-Tempini ML, Hillis AE, Weintraub S, Kertesz A, Mendez M, Cappa SF. Classiffication of primary progressive aphasia and its variants. Neurology. 2011;76:1006-14.
  • Griffith HR, Stewart CC, Den Hollander JA. Proton magnetic resonance spectroscopy in dementias and mild cognitive impairment. International Review of Neurobiology. 2009;84:105-31.
  • Grossman M. Multimodal comparative studies of neurodegenerative diseases. J Alzheimers Dis. 2013;33(01):S379-83.
  • Hermann N, Black S, Li A, Lanctot KL. Discontinuing cholinesterase inhibitors: results of a survey of Canadian dementia experts. Int Psychogeuratr. 2011:23(4):539-45.
  • Inouye SK. Delirium in older persons. N Eng J Med. 2006;354:1157:65.
  • Jellinger KA. Neuropathology of sporadic Parkinson’s disease: evaluation and changes of concepts. Mov Disord. 2012;27:8.
  • Kieburtz K, Wunderle KB. Parkinson’s disease: evidence for environmental risk factors. Mov Disord. 2013;28:8.
  • Kulisevsky J, Luquin MR, Arbelo JM, Burguera JA, Carrillo F, Castro A. Enfermedad de Parkinson avanzada. Características clínicas y tratamiento. Neurología. 2013;28(8):503-21.
  • Loy CT, Schofield PR, Turner AM, Kwok JB. Genetics of dementia. The Lancet. 2013;383:828-40.
  • Marín Carmona M, Álvarez Fernández B. Demencia tipo Alzheimer. Tratado de neuropsicogeriatría. Madrid: SEGG; 2010. p. 214-238.
  • Mass A, Reichmann H. Sleep and non-motor symptoms in Parkinson’s disease. J Neural Transm. 2013;120:565-9.
  • Massoud F, Gauthier S. Update on the pharmacological treatment for Alzheimer’s Disease. Current Neuropharmacology. 2010;8:69-80.
  • McKeith I, Cummings JL. Behavioural changes and psychological symptoms in dementia disorders. Lancet Neurol. 2005;4:735-42.
  • Miyasaki JM, Shannon K, Voon V, Ravina B, Kleiner-Fisman G, Anderson K. Quality Standards Subcommittee of the American Academy of Neurology. Practice parameter: evaluation and treatment of depression, psychosis, and dementia in Parkinson disease (an evidence based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2006;66(7):996-1002.
  • Molinuevo JL. Papel de los biomarcadores en el diagnóstico precoz de la enfermedad de Alzheimer. Rev Esp Geriatr y Gerontol. 2011:46Supl1:39-41.
  • Molinuevo JL. Memantina: el valor de la terapia combinada. Rev Neurol. 2011;52(2):95:100.
  • Muller T. Drug therapy in patients with Parkinson’s disease. Translational Neurodegenerative. 2012;1:10-22.
  • Noyce AJ, Bestwick JP, Silveira-Moriyama L, Hawkes CH, Giovannoni G, Lees AJ. Meta-analysis of early nonmotor features and risk factors for Parkinson disease. Ann Neurol. 2012;72:893.
  • Oldenbeuving AW, de Kort PL, Jansen BP, Kappelle LJ, Roks G. A pilot study of rivastigmine in the treatment of delirium after a stroke: a safe alternative. BMC Neurol. 2008;20(8):34.
  • Osing C, Reichmann H. Treatment of Parkinson’s disease in the advanced stage. J Neurol Transm. 2013;120:523-9.
  • Panegyres PK, Frencham K. Course and causes of suspected dementia in young adults: a longitudinal study. Am J Alzheimer’s Dis Other Deme. 2007;22(1):48-56.
  • Patel L, Grossberg GT. Combination therapy for Alzheimer’s disease. Drugs Aging. 2011;1;28(7):539-46.
  • Petersen RC, Roberts RO, Knopman DS, Boeve BF, Geda YE, Ivnik RJ. Mild cognitive impairment: ten years later. Arch Neu-rol. 2009;66(12):1447-55.
  • Piguet O, Hornberger M, Mioshi E, Hodges JR. Behavioural variant frontotemporal dementia: diagnosis, clinical staging and management. Lancet Neurol. 2011;10:162-72.
  • Poewe W, Gauthier S, Aarsland D, Leverenz JB, Barone P, Weintraub D. Diagnosis and management of Parkinson’s disease dementia. Int J Clin Pract. 2008;62(10):1581-7.
  • Popeo DM. Delirium in older adults. Mt Sinai J Med. 2011;78(4):571-82.
  • Poulopoulos M, Levy OA, Alcalay RN. The neuropathology of genetic Parkinson’s disease. Mov Disord. 2012;27:831.
  • Reisberg B, Doody R, Soffler A, Schmitt F, Ferris S, Mobius HJ. Memantine in moderate to severe Alzheimer’s Disease. N Engl J Med. 2003;348: 1333-41.
  • Sosa-Ortiz AL, Acosta-Castillo I, Prince MJ. Epidemiology of dementias and Alzheimer’s disease. Arch Med Res. 2012;43:600-8.
  • Vidán MT, Sánchez E, Alonso M, Montero B, Ortiz J, Serra A. An intervention integrated into daily clinical practice reduces the incidence of delirium during hospitalization in elderly patients. J Am Geriatr Soc. 2009;57:2029-36.
  • Vlaar AM, van Kroonenburgh MJ, Kessels AG, Weber WE. Meta-analysis of the literature on diagnostic accuracy of SPECT in parkinsonian syn-dromes. BMC Neurology 2007;7:27-39.
  • Waldemar G, Dubois B, Emre M, Georges J, McKeith IG, Rossor M. Recommendations for diagnosis and management of Alzheimer’s disease and other disorders associated with dementia: EFNS guideline. Eur J Neurol. 2007;14:1-26.
  • Weimer D, Sager MA. Early identification and treatment of Alzheimer’s disease: social and fiscal outcomes. Alzheimer Dement. 2009;5(3):215-26.
  • Weintrraub D, Hurtig H. Presentation and management of psychosis in Parkinson’s disease and dementia with Lewy bodies. Am J Psychiatry. 2007;164:1491-8.
  • Wong CL. Does this patient have delirium? Value of bedside instruments. JAMA. 2010;304(7):779-86.
  • Young J, Inouye S. Delirium in older people. Clinical Review. BMJ. 2007;334:842-6.
  • Young J, Murthy L, Westby M, Akunne A, O’Mahony R; Guideline Development Group. Diagnosis, prevention, and management of delirium: summary of NICE guidance. BMJ. 2010;28(341):3704.