Diseño de un esquema de seguimiento según el riesgo de recidiva en pacientes con cáncer de riñón tratados con cirugía

  1. Polanco Pujol, Lucia
Dirigée par:
  1. Carlos Hernández Fernández Directeur
  2. Felipe Herranz Amo Directeur

Université de défendre: Universidad Complutense de Madrid

Fecha de defensa: 05 mars 2021

Jury:
  1. Luis Antonio Álvarez-Sala Walther President
  2. E. Lledó García Secrétaire
  3. Carlos Llorente Abarca Rapporteur
  4. B. Miñana López Rapporteur
  5. Carmen González Enguita Rapporteur
Département:
  1. Cirugía

Type: Thèses

Résumé

Renal cell carcinoma (RCC) represent 2-3% of all malignancies, with a progressive increase in its incidence worldwide. More than 300,000 patients are diagnosed annually, in part due to the development of imaging techniques such ultrasound or tomography, which have led to these tumors being increasingly diagnosed in more localized stages. Surgical treatment is the standard of treatment for non-metastatic kidney tumors; The European Association of Urology (EAU) recommend laparoscopic or open partial nephrectomy in stages cT1 and radical nephrectomy in cT2 not treatable with partial nephrectomy. Follow-up is crucial to detect recurrence; however, there is no consensus on the follow-up protocol after nephrectomy. Thus, there is variability at the time of follow-up, and the recommendations of the clinical guidelines presenting a low level of scientific evidence. Our aim is to design a follow-up protocol based on pathological variables according to the risk of recurrence. As secondary objectives, are to establish recurrence pattern and to identify pathological prognostic variables related to recurrence...