Evaluación neuropsicológica en pacientes con fibromialgiaperfil cognitivo

  1. ARJONA GONZÁLEZ, MANUEL EDUARDO
Supervised by:
  1. Melchor Álvarez de Mon Soto Director

Defence university: Universidad de Alcalá

Fecha de defensa: 28 September 2017

Committee:
  1. María Julia Araceli Buján Varela Chair
  2. Silvia Jiménez Sánchez Secretary
  3. M. Leticia Muñoz Zamarrón Committee member

Type: Thesis

Teseo: 528216 DIALNET lock_openTESEO editor

Abstract

OBJECTIVE: Assessment of cognitive function in patients with fibromyalgia syndrome (FM) and general population and its association to syndrome severity, comorbidities and gender. METHOD: Transversal study of cases and controls of cognitive disorder in patients with FM. Neuropsychological assessment was conducted on 81 FM patients (74 women and 7 men) and 160 healthy controls, grouped by age and education level (20 subgroups). Assessment included a full battery of neuropsychological tests using Barcelona Abbreviated Test and Fybromyalgia Impact Questionnaire. Statistical analysis strategy (parametric and non parametric tests) was used to assess qualititative categorical variables (dichotomous variables) and quantitative variables (continuous variables) for both global cognitive function and cognitive domains. RESULTS: Statistical meaningful differences in global cognitive function and cognitive domains were found between FM patients and controls. There were no statistical meaningful differences in performance between FM patients with and without comorbidities, gender and syndrome severity. CONCLUSION: Mild cognitive disorder (GDS-3 Reisberg Scale) is apparent in FM. Cognitive domains like memory, attention and executive function are affected. There is no difference in cognitive function depending on gender, comorbidities and severity of syndrome.