Sarcoma de Kaposi iatrogénico diseminado con debut en encía maxilara propósito de un caso

  1. Marc Agea Martínez
  2. Manuel Alejandro Tousidonis Rial
  3. C. Navarro Cuéllar
  4. Raúl Antúnez Conde
  5. Dafne Gascón Alonso
  6. José Ignacio Salmerón Escobar
Revista:
Revista española de cirugía oral y maxilofacial: Publicación Oficial de la Sociedad Española de Cirugía Oral y Maxilofacial

ISSN: 1130-0558 2173-9161

Ano de publicación: 2021

Volume: 43

Número: 2

Páxinas: 55-58

Tipo: Artigo

DOI: 10.20986/RECOM.2020.1158/2020 DIALNET GOOGLE SCHOLAR

Outras publicacións en: Revista española de cirugía oral y maxilofacial: Publicación Oficial de la Sociedad Española de Cirugía Oral y Maxilofacial

Resumo

ABSTRACT Kaposi's Sarcoma (KS) is a multifocal neoplasm of cells derived from the lymphatic endothelium infected with the Human Herpes Virus 8 (HHV-8). Four clinical subtypes are described, which are histologically indistinguishable, differ in epidemiology and prognosis: classic, iatrogenic, endemic and epidemic. Involvement of the oral cavity is rare in the iatrogenic type and exceptional as a clinical debut. The diagnosis requires histological confirmation with immunohistochemistry. Oral involvement is associated with disseminated disease, with diagnostic suspicion and biopsy taking being essential for early diagnosis and correct staging, due to the important therapeutic and prognostic implications. The clinical case of a 41-year-old male evaluated for a tumor in the attached gingiva with previous periodontal treatment and a history of kidney transplantation is described. Excisional biopsy was performed with a diagnosis of KS, which after completing the study confirmed disseminated iatrogenic-type KS requiring a change in immunosuppressive medication and 6 cycles of chemotherapy treatment with complete response.

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