Cistatina C en la evaluación de la función renal
- María Fernández García
- Elisabeth Coll Torres
- Salvador Ventura Pedret
- Carmen Bermudo Guitarte
- María Cruz Cárdenas Fernández
- Mariano Cortés Rius
- Miguel García Montes
- Cecilia Martínez Brú
- David Pérez Surribas
- Teresa Rodríguez González
- Carmen Valldecabres Ortiz
- José Antonio Viedma Contreras
- Edgar Zapico Muñiz
ISSN: 1888-4008
Year of publication: 2011
Volume: 4
Issue: 1
Pages: 50-62
Type: Article
More publications in: Revista del laboratorio clínico
Abstract
Glomerular filtration is the best index for assessing renal function. Despite being subjected to several sources of variability, serum creatinine is the most common glomerular filtration marker in use. Cystatin C is a low molecular weight protein which is more sensitive than creatinine, particularly for the identification of initial small decreases in renal function. The use of cystatin C in certain groups of patients such as elderly, children or diabetics appears to provide more information than creatinine. However, serum cystatin C can be influenced by non-renal factors. Currently, there is not enough scientific evidence to recommend the use of cystatin C to assess renal function instead of creatinine and creatinine equations.