El papel de la genética en la aparición y desarrollo de la periodontitis. II:polimorfismos asociados
- Rodrigo Gómez, D.
- Oteo Calatayud, A.
- Alonso Rosado, M.A.
- Bascones Martínez, Antonio
ISSN: 1699-6585
Year of publication: 2008
Volume: 20
Issue: 2
Pages: 121-130
Type: Article
More publications in: Avances en periodoncia e implantología oral
Sustainable development goals
Abstract
Periodontitis is a multifactorial disease in which the interaction of periodontal pathogens with the host immune defense machanism characterizes an inflamatory reaction that affects the attachment apparatus of the tooth. Multifactorial diseases normally involve complex genetic-enviromental interactions. The type of genetic variations described in these diseases are defined as polymorphisms. Different polymorphysm have been observed and normally the phenotypic consequences are limited. In the first part of this review the evidence of association between Periodontitis and Genetics is analyzed. In the second part a special focus will be dedicated to research on polymorphysm and the clinical projection related to Periodontitis.